Differential rates of age of seizure onset between sexes and between hemispheres?

Esther Strauss, Michael Hunter, Bruce P. Hermann, David W. Loring, Max R. Trenerry, William B. Barr, Gordon J. Chelune, Kenneth Perrine, Michael Westerveld, Juhn Wada

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

In a descriptive analysis of 158 patients with temporal lobe epilepsy, Taylor reported that the age of first seizure varied systematically as a function of laterality and sex. We conducted inferential analyses of Taylor's original data which (1) provided support for his proposal of disproportionate left hemisphere vulnerability to seizure onset in early life, but (2) failed to provide evidence of sex differences in age of onset of unilateral seizures. Examination of these effects in a larger sample of 844 patients drawn from the Bozeman Epilepsy Consortium provided some additional support for findings from the inferential analysis. Specifically, the left hemisphere appeared more vulnerable to seizure onset in childhood, this increased vulnerability extending to about age 5 years. Age of onset of seizures was not different when males and females were compared. Thus, reanalysis of Taylor's original data as well as examination of data from a larger, more contemporary sample suggest that seizure onset varies as a function of laterality, but not sex.

Original languageEnglish (US)
Pages (from-to)428-434
Number of pages7
JournalJournal of the International Neuropsychological Society
Volume3
Issue number5
StatePublished - Sep 1997

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Age of Onset
Seizures
Temporal Lobe Epilepsy
Sex Characteristics
Epilepsy

Keywords

  • Age of seizure onset
  • Epilepsy
  • Laterality
  • Sex

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Psychiatry and Mental health
  • Neuroscience(all)
  • Psychology(all)

Cite this

Strauss, E., Hunter, M., Hermann, B. P., Loring, D. W., Trenerry, M. R., Barr, W. B., ... Wada, J. (1997). Differential rates of age of seizure onset between sexes and between hemispheres? Journal of the International Neuropsychological Society, 3(5), 428-434.

Differential rates of age of seizure onset between sexes and between hemispheres? / Strauss, Esther; Hunter, Michael; Hermann, Bruce P.; Loring, David W.; Trenerry, Max R.; Barr, William B.; Chelune, Gordon J.; Perrine, Kenneth; Westerveld, Michael; Wada, Juhn.

In: Journal of the International Neuropsychological Society, Vol. 3, No. 5, 09.1997, p. 428-434.

Research output: Contribution to journalArticle

Strauss, E, Hunter, M, Hermann, BP, Loring, DW, Trenerry, MR, Barr, WB, Chelune, GJ, Perrine, K, Westerveld, M & Wada, J 1997, 'Differential rates of age of seizure onset between sexes and between hemispheres?', Journal of the International Neuropsychological Society, vol. 3, no. 5, pp. 428-434.
Strauss E, Hunter M, Hermann BP, Loring DW, Trenerry MR, Barr WB et al. Differential rates of age of seizure onset between sexes and between hemispheres? Journal of the International Neuropsychological Society. 1997 Sep;3(5):428-434.
Strauss, Esther ; Hunter, Michael ; Hermann, Bruce P. ; Loring, David W. ; Trenerry, Max R. ; Barr, William B. ; Chelune, Gordon J. ; Perrine, Kenneth ; Westerveld, Michael ; Wada, Juhn. / Differential rates of age of seizure onset between sexes and between hemispheres?. In: Journal of the International Neuropsychological Society. 1997 ; Vol. 3, No. 5. pp. 428-434.
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