TY - JOUR
T1 - Dietary Fiber Supplements
T2 - Effects in Obesity and Metabolic Syndrome and Relationship to Gastrointestinal Functions
AU - Papathanasopoulos, Athanasios
AU - Camilleri, Michael
N1 - Funding Information:
Funding Supported in part by grants R01 DK 67071 and K24 DK 02638 from the National Institutes of Health (to M.C.) and an international grant from the Hellenic Society of Gastroenterology (to A.P.).
PY - 2010/1
Y1 - 2010/1
N2 - Dietary fiber is a term that reflects a heterogeneous group of natural food sources, processed grains, and commercial supplements. Several forms of dietary fiber have been used as complementary or alternative agents in the management of manifestations of the metabolic syndrome, including obesity. Not surprisingly, there is a great variation in the biological efficacy of dietary fiber in the metabolic syndrome and body weight control. Diverse factors and mechanisms have been reported as mediators of the effects of dietary fiber on the metabolic syndrome and obesity. Among this array of mechanisms, the modulation of gastric sensorimotor influences appears to be crucial for the effects of dietary fiber but also quite variable. This report focuses on the role, mechanism of action, and benefits of different forms of fiber and supplements on obesity and the metabolic syndrome, glycemia, dyslipidemia, and cardiovascular risk and explores the effects of dietary fiber on gastric sensorimotor function and satiety in mediating these actions of dietary fiber.
AB - Dietary fiber is a term that reflects a heterogeneous group of natural food sources, processed grains, and commercial supplements. Several forms of dietary fiber have been used as complementary or alternative agents in the management of manifestations of the metabolic syndrome, including obesity. Not surprisingly, there is a great variation in the biological efficacy of dietary fiber in the metabolic syndrome and body weight control. Diverse factors and mechanisms have been reported as mediators of the effects of dietary fiber on the metabolic syndrome and obesity. Among this array of mechanisms, the modulation of gastric sensorimotor influences appears to be crucial for the effects of dietary fiber but also quite variable. This report focuses on the role, mechanism of action, and benefits of different forms of fiber and supplements on obesity and the metabolic syndrome, glycemia, dyslipidemia, and cardiovascular risk and explores the effects of dietary fiber on gastric sensorimotor function and satiety in mediating these actions of dietary fiber.
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U2 - 10.1053/j.gastro.2009.11.045
DO - 10.1053/j.gastro.2009.11.045
M3 - Review article
C2 - 19931537
AN - SCOPUS:72249115973
SN - 0016-5085
VL - 138
SP - 65-72.e2
JO - Gastroenterology
JF - Gastroenterology
IS - 1
ER -