Abstract
Diastolic filling of the heart is a complex sequence of multiple inter-related events consisting of processes such as ventricular relaxation, erectile coronary effect, visco-elastic forces of the myocardium, ventricular interaction, myocardial stress strain relationships, pericardial restraint, passive filling, and atrial contraction. However, in order to understand diastolic filling from a clinical aspect, a simplified foundation can be used which divides the cardiac cycle into contraction, relaxation, passive filling, and filling at atrial contraction. The mitral flow velocity curves are representative of the relative driving pressure between left atrium and left ventricle and allow one to grade the progression of diastolic dysfunction which occurs in disease states. Doppler tissue imaging is necessary as a surrogate of ventricular relaxation to further determine the stages of diastolic dysfunction in patients with preserved ejection fraction. These Doppler flow velocity curves can be applied to understanding diastolic filling of the heart in patients with both reduced ejection fraction and preserved ejection fraction.
| Original language | English (US) |
|---|---|
| Journal | Journal of Cardiology |
| DOIs | |
| State | Published - Jan 1 2019 |
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Keywords
- Diastole
- Doppler echocardiography
- Ventricular relaxation
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Diastology for the clinician. / Nishimura, Rick A.; Borlaug, Barry A.
In: Journal of Cardiology, 01.01.2019.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Diastology for the clinician
AU - Nishimura, Rick A.
AU - Borlaug, Barry A
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Diastolic filling of the heart is a complex sequence of multiple inter-related events consisting of processes such as ventricular relaxation, erectile coronary effect, visco-elastic forces of the myocardium, ventricular interaction, myocardial stress strain relationships, pericardial restraint, passive filling, and atrial contraction. However, in order to understand diastolic filling from a clinical aspect, a simplified foundation can be used which divides the cardiac cycle into contraction, relaxation, passive filling, and filling at atrial contraction. The mitral flow velocity curves are representative of the relative driving pressure between left atrium and left ventricle and allow one to grade the progression of diastolic dysfunction which occurs in disease states. Doppler tissue imaging is necessary as a surrogate of ventricular relaxation to further determine the stages of diastolic dysfunction in patients with preserved ejection fraction. These Doppler flow velocity curves can be applied to understanding diastolic filling of the heart in patients with both reduced ejection fraction and preserved ejection fraction.
AB - Diastolic filling of the heart is a complex sequence of multiple inter-related events consisting of processes such as ventricular relaxation, erectile coronary effect, visco-elastic forces of the myocardium, ventricular interaction, myocardial stress strain relationships, pericardial restraint, passive filling, and atrial contraction. However, in order to understand diastolic filling from a clinical aspect, a simplified foundation can be used which divides the cardiac cycle into contraction, relaxation, passive filling, and filling at atrial contraction. The mitral flow velocity curves are representative of the relative driving pressure between left atrium and left ventricle and allow one to grade the progression of diastolic dysfunction which occurs in disease states. Doppler tissue imaging is necessary as a surrogate of ventricular relaxation to further determine the stages of diastolic dysfunction in patients with preserved ejection fraction. These Doppler flow velocity curves can be applied to understanding diastolic filling of the heart in patients with both reduced ejection fraction and preserved ejection fraction.
KW - Diastole
KW - Doppler echocardiography
KW - Ventricular relaxation
UR - http://www.scopus.com/inward/record.url?scp=85063215273&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85063215273&partnerID=8YFLogxK
U2 - 10.1016/j.jjcc.2019.03.002
DO - 10.1016/j.jjcc.2019.03.002
M3 - Review article
JO - Journal of cardiography. Supplement
JF - Journal of cardiography. Supplement
SN - 0914-5087
ER -