Diastolic stress echocardiography: A novel noninvasive diagnostic test for diastolic dysfunction using supine bicycle exercise Doppler echocardiography

Jong Won Ha, Jae Kuen Oh, Patricia Pellikka, Steve R. Ommen, Vicky L. Stussy, Kent R Bailey, James B. Seward, A. Jamil Tajik

Research output: Contribution to journalArticle

184 Citations (Scopus)

Abstract

Left ventricular filling pressures can be estimated reliably by combining mitral inflow early diastolic velocity (E) and annulus velocity (E′). An increased E/E′ ratio reflects elevated filling pressures and may be useful in assessing an abnormal increase in filling pressures for patients with diastolic dysfunction. The purpose of this study was to evaluate the feasibility of supine bicycle exercise Doppler echocardiography for assessing left ventricular diastolic pressure during exercise. Mitral inflow and septal mitral annulus velocities were measured at rest and during supine bicycle exercise (25-W 3-minute increments) in 45 patients (19 men; mean age, 59 years) referred for evaluation of exertional dyspnea. None had echocardiographic or electrocardiographic evidence of myocardial ischemia with exercise. Patients were classified according to E/E′ ratio at rest: 26 had E/E′ ≤ 10 at rest (group 1) and 19 had E/E′ > 10 (group 2). For group 1, 17 had no increase in E/E′ during exercise (group 1A) and 9 did (group 1B). For group 2, E/E′ did not increase during exercise. Despite different responses of E/E′, there was no significant difference in changes of mitral inflow indices (E, A, E/A, deceleration time) between groups. Although the percentage of dyspnea as a primary reason for stopping exercise was similar for the groups, exercise duration was significantly shorter for groups 1B (7.2 ± 2.5 minutes) and 2 (7.1 ± 3.3 minutes) than in group 1A (10.4 ± 3.7 minutes, P =. 0129). Diastolic stress echocardiography using a supine bicycle is technically feasible for demonstrating changes in E/E′ (filling pressure) with exercise. Our preliminary results suggest the hemodynamic consequences of exercise-induced increase in diastolic filling pressure can be demonstrated noninvasively with exercise Doppler echocardiography.

Original languageEnglish (US)
Pages (from-to)63-68
Number of pages6
JournalJournal of the American Society of Echocardiography
Volume18
Issue number1
DOIs
StatePublished - Jan 2005

Fingerprint

Stress Echocardiography
Doppler Echocardiography
Routine Diagnostic Tests
Exercise
Ventricular Pressure
Pressure
Dyspnea
Blood Pressure
Deceleration
Myocardial Ischemia
Hemodynamics

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Diastolic stress echocardiography : A novel noninvasive diagnostic test for diastolic dysfunction using supine bicycle exercise Doppler echocardiography. / Ha, Jong Won; Oh, Jae Kuen; Pellikka, Patricia; Ommen, Steve R.; Stussy, Vicky L.; Bailey, Kent R; Seward, James B.; Tajik, A. Jamil.

In: Journal of the American Society of Echocardiography, Vol. 18, No. 1, 01.2005, p. 63-68.

Research output: Contribution to journalArticle

@article{c487dd906615494c916794fb8b59608b,
title = "Diastolic stress echocardiography: A novel noninvasive diagnostic test for diastolic dysfunction using supine bicycle exercise Doppler echocardiography",
abstract = "Left ventricular filling pressures can be estimated reliably by combining mitral inflow early diastolic velocity (E) and annulus velocity (E′). An increased E/E′ ratio reflects elevated filling pressures and may be useful in assessing an abnormal increase in filling pressures for patients with diastolic dysfunction. The purpose of this study was to evaluate the feasibility of supine bicycle exercise Doppler echocardiography for assessing left ventricular diastolic pressure during exercise. Mitral inflow and septal mitral annulus velocities were measured at rest and during supine bicycle exercise (25-W 3-minute increments) in 45 patients (19 men; mean age, 59 years) referred for evaluation of exertional dyspnea. None had echocardiographic or electrocardiographic evidence of myocardial ischemia with exercise. Patients were classified according to E/E′ ratio at rest: 26 had E/E′ ≤ 10 at rest (group 1) and 19 had E/E′ > 10 (group 2). For group 1, 17 had no increase in E/E′ during exercise (group 1A) and 9 did (group 1B). For group 2, E/E′ did not increase during exercise. Despite different responses of E/E′, there was no significant difference in changes of mitral inflow indices (E, A, E/A, deceleration time) between groups. Although the percentage of dyspnea as a primary reason for stopping exercise was similar for the groups, exercise duration was significantly shorter for groups 1B (7.2 ± 2.5 minutes) and 2 (7.1 ± 3.3 minutes) than in group 1A (10.4 ± 3.7 minutes, P =. 0129). Diastolic stress echocardiography using a supine bicycle is technically feasible for demonstrating changes in E/E′ (filling pressure) with exercise. Our preliminary results suggest the hemodynamic consequences of exercise-induced increase in diastolic filling pressure can be demonstrated noninvasively with exercise Doppler echocardiography.",
author = "Ha, {Jong Won} and Oh, {Jae Kuen} and Patricia Pellikka and Ommen, {Steve R.} and Stussy, {Vicky L.} and Bailey, {Kent R} and Seward, {James B.} and Tajik, {A. Jamil}",
year = "2005",
month = "1",
doi = "10.1016/j.echo.2004.08.033",
language = "English (US)",
volume = "18",
pages = "63--68",
journal = "Journal of the American Society of Echocardiography",
issn = "0894-7317",
publisher = "Mosby Inc.",
number = "1",

}

TY - JOUR

T1 - Diastolic stress echocardiography

T2 - A novel noninvasive diagnostic test for diastolic dysfunction using supine bicycle exercise Doppler echocardiography

AU - Ha, Jong Won

AU - Oh, Jae Kuen

AU - Pellikka, Patricia

AU - Ommen, Steve R.

AU - Stussy, Vicky L.

AU - Bailey, Kent R

AU - Seward, James B.

AU - Tajik, A. Jamil

PY - 2005/1

Y1 - 2005/1

N2 - Left ventricular filling pressures can be estimated reliably by combining mitral inflow early diastolic velocity (E) and annulus velocity (E′). An increased E/E′ ratio reflects elevated filling pressures and may be useful in assessing an abnormal increase in filling pressures for patients with diastolic dysfunction. The purpose of this study was to evaluate the feasibility of supine bicycle exercise Doppler echocardiography for assessing left ventricular diastolic pressure during exercise. Mitral inflow and septal mitral annulus velocities were measured at rest and during supine bicycle exercise (25-W 3-minute increments) in 45 patients (19 men; mean age, 59 years) referred for evaluation of exertional dyspnea. None had echocardiographic or electrocardiographic evidence of myocardial ischemia with exercise. Patients were classified according to E/E′ ratio at rest: 26 had E/E′ ≤ 10 at rest (group 1) and 19 had E/E′ > 10 (group 2). For group 1, 17 had no increase in E/E′ during exercise (group 1A) and 9 did (group 1B). For group 2, E/E′ did not increase during exercise. Despite different responses of E/E′, there was no significant difference in changes of mitral inflow indices (E, A, E/A, deceleration time) between groups. Although the percentage of dyspnea as a primary reason for stopping exercise was similar for the groups, exercise duration was significantly shorter for groups 1B (7.2 ± 2.5 minutes) and 2 (7.1 ± 3.3 minutes) than in group 1A (10.4 ± 3.7 minutes, P =. 0129). Diastolic stress echocardiography using a supine bicycle is technically feasible for demonstrating changes in E/E′ (filling pressure) with exercise. Our preliminary results suggest the hemodynamic consequences of exercise-induced increase in diastolic filling pressure can be demonstrated noninvasively with exercise Doppler echocardiography.

AB - Left ventricular filling pressures can be estimated reliably by combining mitral inflow early diastolic velocity (E) and annulus velocity (E′). An increased E/E′ ratio reflects elevated filling pressures and may be useful in assessing an abnormal increase in filling pressures for patients with diastolic dysfunction. The purpose of this study was to evaluate the feasibility of supine bicycle exercise Doppler echocardiography for assessing left ventricular diastolic pressure during exercise. Mitral inflow and septal mitral annulus velocities were measured at rest and during supine bicycle exercise (25-W 3-minute increments) in 45 patients (19 men; mean age, 59 years) referred for evaluation of exertional dyspnea. None had echocardiographic or electrocardiographic evidence of myocardial ischemia with exercise. Patients were classified according to E/E′ ratio at rest: 26 had E/E′ ≤ 10 at rest (group 1) and 19 had E/E′ > 10 (group 2). For group 1, 17 had no increase in E/E′ during exercise (group 1A) and 9 did (group 1B). For group 2, E/E′ did not increase during exercise. Despite different responses of E/E′, there was no significant difference in changes of mitral inflow indices (E, A, E/A, deceleration time) between groups. Although the percentage of dyspnea as a primary reason for stopping exercise was similar for the groups, exercise duration was significantly shorter for groups 1B (7.2 ± 2.5 minutes) and 2 (7.1 ± 3.3 minutes) than in group 1A (10.4 ± 3.7 minutes, P =. 0129). Diastolic stress echocardiography using a supine bicycle is technically feasible for demonstrating changes in E/E′ (filling pressure) with exercise. Our preliminary results suggest the hemodynamic consequences of exercise-induced increase in diastolic filling pressure can be demonstrated noninvasively with exercise Doppler echocardiography.

UR - http://www.scopus.com/inward/record.url?scp=11144239323&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=11144239323&partnerID=8YFLogxK

U2 - 10.1016/j.echo.2004.08.033

DO - 10.1016/j.echo.2004.08.033

M3 - Article

C2 - 15637491

AN - SCOPUS:11144239323

VL - 18

SP - 63

EP - 68

JO - Journal of the American Society of Echocardiography

JF - Journal of the American Society of Echocardiography

SN - 0894-7317

IS - 1

ER -