Diaphragm dysfunction and respiratory insufficiency after upper abdominal surgery.

J. Sprung, E. Y. Cheng, N. Nimphius, R. D. Hubmayr, J. R. Rodarte, J. P. Kampine

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

This study was designed to determine the contribution of diaphragm dysfunction and pain to respiratory insufficiency after upper abdominal surgery. Respiratory insufficiency and postoperative pain in humans were evaluated by pulse oximetry, pulmonary function tests, and a visual analog scale. Diaphragm shortening in dogs was evaluated with biplane videoroentgenography. In humans, despite reasonable pain control, pulmonary function, as reflected in forced vital capacity (FVC), forced expiratory volume in one second (FEV1) and arterial oxygen saturation (SpO2) were significantly reduced on the first postoperative day. Improved pain control was not associated with improvements in FVC or FEV1. In the dogs, diaphragm shortening and tidal volume were significantly reduced in the immediate postoperative period. Phrenic nerve stimulation immediately after surgery resulted in supramaximal diaphragm shortening, which indicated neither the diaphragm nor phrenic nerves were significantly injured by surgical manipulation. Diaphragm dysfunction has a major role in postoperative pulmonary insufficiency; an afferent-mediated reflex inhibition of the phrenic nerves may be responsible.

Original languageEnglish (US)
Pages (from-to)5-12
Number of pages8
JournalPlucne Bolesti
Volume43
Issue number1-2
StatePublished - Jan 1991
Externally publishedYes

Fingerprint

Diaphragm
Respiratory Insufficiency
Phrenic Nerve
Vital Capacity
Pain
Dogs
Lung
Oximetry
Respiratory Function Tests
Tidal Volume
Forced Expiratory Volume
Postoperative Pain
Visual Analog Scale
Postoperative Period
Reflex
Oxygen

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Sprung, J., Cheng, E. Y., Nimphius, N., Hubmayr, R. D., Rodarte, J. R., & Kampine, J. P. (1991). Diaphragm dysfunction and respiratory insufficiency after upper abdominal surgery. Plucne Bolesti, 43(1-2), 5-12.

Diaphragm dysfunction and respiratory insufficiency after upper abdominal surgery. / Sprung, J.; Cheng, E. Y.; Nimphius, N.; Hubmayr, R. D.; Rodarte, J. R.; Kampine, J. P.

In: Plucne Bolesti, Vol. 43, No. 1-2, 01.1991, p. 5-12.

Research output: Contribution to journalArticle

Sprung, J, Cheng, EY, Nimphius, N, Hubmayr, RD, Rodarte, JR & Kampine, JP 1991, 'Diaphragm dysfunction and respiratory insufficiency after upper abdominal surgery.', Plucne Bolesti, vol. 43, no. 1-2, pp. 5-12.
Sprung J, Cheng EY, Nimphius N, Hubmayr RD, Rodarte JR, Kampine JP. Diaphragm dysfunction and respiratory insufficiency after upper abdominal surgery. Plucne Bolesti. 1991 Jan;43(1-2):5-12.
Sprung, J. ; Cheng, E. Y. ; Nimphius, N. ; Hubmayr, R. D. ; Rodarte, J. R. ; Kampine, J. P. / Diaphragm dysfunction and respiratory insufficiency after upper abdominal surgery. In: Plucne Bolesti. 1991 ; Vol. 43, No. 1-2. pp. 5-12.
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