Abstract
Meta-analysis refers to the use of statistical tools to combine and compare the results of multiple studies on particular outcomes on interest. Use of meta-analysis in the medical literature, including the field of gastroenterology, has been increasing. Conducting high-quality meta-analysis can be challenging. Similarly understanding published meta-analyses can be difficult. In this chapter, we will present several case studies on meta-analyses in gastroenterology. We will use these studies to shed light on several key factors in meta-analyses. These factors include the importance of choosing the appropriate inclusion and exclusion criteria, deciding on the best meta-meter of interest, recognizing and dealing with duplicate cohorts, and using direct and indirect comparisons. Our goal is to show how meta-analyses can be great tools for providing evidence-based results that can have a significant impact on clinical practice in the field of gastroenterology.
Original language | English (US) |
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Title of host publication | Diagnostic Meta-Analysis |
Subtitle of host publication | A Useful Tool for Clinical Decision-Making |
Publisher | Springer International Publishing |
Pages | 249-261 |
Number of pages | 13 |
ISBN (Electronic) | 9783319789668 |
ISBN (Print) | 9783319789651 |
DOIs | |
State | Published - Jan 1 2018 |
Keywords
- Clinical research
- Endoscopy
- Epidemiology
- Gastroenterology
- Meta-analysis
- Systematic review
ASJC Scopus subject areas
- General Medicine
- General Agricultural and Biological Sciences
- General Biochemistry, Genetics and Molecular Biology
- General Psychology