Diagnostic approach to small bowel involvement in inflammatory bowel disease: View of the endoscopist

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Recent advances in endoscopic small bowel (SB) techniques have revolutionalized the diagnostic approach of patients with suspected or known inflammatory bowel disease (IBD). Wireless capsule endoscopy (WCE) has become an important diagnostic tool for the evaluation of suspected CD of the SB or in patients with known IBD to rule out SB involvement. The greatest utility of WCE has been observed in cases of suspected CD, where the initial evaluation with traditional radiographic and endoscopic studies has failed to establish the diagnosis. WCE can detect early SB lesions that can be overlooked by traditional radiological studies. The sensitivity of diagnosing SB CD by WCE is superior to other endoscopic or radiological methods such as push enteroscopy, computed tomography or magnetic resonance enteroclysis. The utility of WCE in patients with known CD, IBD unclassified (IBDU) and a select group of patients with ulcerative colitis (UC) can better define the diagnosis and extent of the disease and may lead to reclassification of IBD from UC/IBDU to definitive CD. In addition, previously diagnosed patients with CD may be found to have more significant disease burden in the SB. This information may facilitate more targeted and effective therapies and potentially lead to better patient outcomes. A disadvantage of WCE is its low specificity and the risk of being retained in a strictured area of the SB. Balloon-assisted enteroscopy has essentially replaced push enteroscopy, and has been used to treat CD strictures, obtain biopsies from areas of SB involvement and even retrieving a retained capsule.

Original languageEnglish (US)
Pages (from-to)476-481
Number of pages6
JournalDigestive Diseases
Volume27
Issue number4
DOIs
StatePublished - Nov 1 2009
Externally publishedYes

Fingerprint

Capsule Endoscopy
Inflammatory Bowel Diseases
Ulcerative Colitis
Capsules
Pathologic Constriction
Magnetic Resonance Spectroscopy
Tomography
Biopsy

Keywords

  • Balloon-assisted enteroscopy
  • Double-balloon enteroscopy
  • Inflammatory bowel disease, small bowel involvement
  • Intraoperative enteroscopy
  • Push enteroscopy
  • Single-balloon enteroscopy
  • Wireless capsule endoscopy

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Diagnostic approach to small bowel involvement in inflammatory bowel disease : View of the endoscopist. / Papadakis, Konstantinos.

In: Digestive Diseases, Vol. 27, No. 4, 01.11.2009, p. 476-481.

Research output: Contribution to journalReview article

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