Diagnosis of Nodal Peripheral T-Cell Lymphomas

Matthew Howard, Ahmet Dogan

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Lymph node-based peripheral T-cell lymphomas are rare and exhibit a morphologic spectrum that overlaps with reactive lymphoid hyperplasia, B-cell lymphomas, and Hodgkin lymphoma, presenting a diagnostic challenge. This review focuses on the major categories of lymph node-based peripheral T-cell lymphomas recognized by the 2008 World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues. Diagnostic strategies for approaching T-cell neoplasms using a combined clinical, morphologic, immunophenotypic, and genetic approach are presented. Practical information to aid in distinguishing peripheral T-cell lymphomas from other hematologic malignancies and benign conditions is provided.

Original languageEnglish (US)
Pages (from-to)955-988
Number of pages34
JournalSurgical Pathology Clinics
Volume3
Issue number4
DOIs
StatePublished - Dec 1 2010

Keywords

  • Anaplastic large cell lymphoma
  • Angioimmunoblastic
  • Lymph node hyperplasia
  • T-cell lymphoma

ASJC Scopus subject areas

  • Surgery
  • Pathology and Forensic Medicine

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