Diagnosis of mesial temporal sclerosis with conventional versus fast spin- echo MR imaging

C. R. Jack, K. N. Krecke, P. H. Luetmer, G. D. Cascino, F. W. Sharbrough, P. C. O'Brien, J. E. Parisi

Research output: Contribution to journalArticle

26 Scopus citations


PURPOSE: To test the accuracy of fast spin-echo (FSE) imaging versus that of double-echo conventional spin-echo (CSE) imaging in identification of the increased hippocampal signal intensity associated with mesial temporal sclerosis (MTS). MATERIALS AND METHODS: Thirty-four subjects who subsequently underwent anterior temporal lobectomy for intractable seizures and in whom the presence or absence of MTS was ascertained with certainty were imaged with CSE and FSE. Three blinded reviewers evaluated the first and second CSE images (CSE1 and CSE2) and the FSE images. RESULTS: CSE1 imaging had lower accuracy than FSE (P = .038) and CSE2 (P = .006) imaging. CSE2 imaging was slightly more accurate than FSE imaging (P = .048). Contrast-to-noise ratios were lower for CSE1 imaging than for CSE2 or FSE imaging (P < .001). CONCLUSION: The FSE sequence evaluated was more time efficient than CSE imaging but slightly less accurate. Therefore, substitution of this sequence for a CSE sequence seems unwarranted.

Original languageEnglish (US)
Pages (from-to)123-127
Number of pages5
Issue number1
StatePublished - Jan 1 1994


  • Brain, abnormalities
  • Epilepsy
  • Magnetic resonance (MR), pulse sequences
  • Magnetic resonance (MR), rapid imaging
  • Seizures

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Diagnosis of mesial temporal sclerosis with conventional versus fast spin- echo MR imaging'. Together they form a unique fingerprint.

  • Cite this