Diagnosis and treatment of viral myocarditis

Jason C. Schultz, Anthony A. Hilliard, Leslie T Jr. Cooper, Charanjit S. Rihal

Research output: Contribution to journalArticle

123 Citations (Scopus)

Abstract

Myocarditis, an inflammatory disease of heart muscle, is an important cause of dilated cardiomyopathy worldwide. Viral infection is also an important cause of myocarditis, and the spectrum of viruses known to cause myocarditis has changed in the past 2 decades. Several new diagnostic methods, such as cardiac magnetic resonance imaging, are useful for diagnosing myocarditis. Endomyocardial biopsy may be used for patients with acute dilated cardiomyopathy associated with hemodynamic compromise, those with life-threatening arrhythmia, and those whose condition does not respond to conventional supportive therapy. Important prognostic variables include the degree of left and right ventricular dysfunction, heart block, and specific histopathological forms of myocarditis. We review diagnostic and therapeutic strategies for the treatment of viral myocarditis. English-language publications in PubMed and references from relevant articles published between January 1, 1985, and August 5, 2008, were analyzed.

Original languageEnglish (US)
Pages (from-to)1001-1009
Number of pages9
JournalMayo Clinic Proceedings
Volume84
Issue number11
DOIs
StatePublished - 2009

Fingerprint

Myocarditis
Dilated Cardiomyopathy
Therapeutics
Right Ventricular Dysfunction
Heart Block
Left Ventricular Dysfunction
Virus Diseases
PubMed
Publications
Cardiac Arrhythmias
Myocardium
Language
Hemodynamics
Magnetic Resonance Imaging
Viruses
Biopsy

Keywords

  • Cardiac magnetic resonance imaging
  • Dilated cardiomyopathy
  • Endomyocardial biopsy
  • Immunotherapy
  • Myocarditis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Diagnosis and treatment of viral myocarditis. / Schultz, Jason C.; Hilliard, Anthony A.; Cooper, Leslie T Jr.; Rihal, Charanjit S.

In: Mayo Clinic Proceedings, Vol. 84, No. 11, 2009, p. 1001-1009.

Research output: Contribution to journalArticle

Schultz, JC, Hilliard, AA, Cooper, LTJ & Rihal, CS 2009, 'Diagnosis and treatment of viral myocarditis', Mayo Clinic Proceedings, vol. 84, no. 11, pp. 1001-1009. https://doi.org/10.4065/84.11.1001
Schultz, Jason C. ; Hilliard, Anthony A. ; Cooper, Leslie T Jr. ; Rihal, Charanjit S. / Diagnosis and treatment of viral myocarditis. In: Mayo Clinic Proceedings. 2009 ; Vol. 84, No. 11. pp. 1001-1009.
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