Diagnosis and treatment of viral myocarditis

Jason C. Schultz, Anthony A. Hilliard, Leslie T. Cooper, Charanjit S. Rihal

Research output: Contribution to journalReview article

135 Scopus citations

Abstract

Myocarditis, an inflammatory disease of heart muscle, is an important cause of dilated cardiomyopathy worldwide. Viral infection is also an important cause of myocarditis, and the spectrum of viruses known to cause myocarditis has changed in the past 2 decades. Several new diagnostic methods, such as cardiac magnetic resonance imaging, are useful for diagnosing myocarditis. Endomyocardial biopsy may be used for patients with acute dilated cardiomyopathy associated with hemodynamic compromise, those with life-threatening arrhythmia, and those whose condition does not respond to conventional supportive therapy. Important prognostic variables include the degree of left and right ventricular dysfunction, heart block, and specific histopathological forms of myocarditis. We review diagnostic and therapeutic strategies for the treatment of viral myocarditis. English-language publications in PubMed and references from relevant articles published between January 1, 1985, and August 5, 2008, were analyzed.

Original languageEnglish (US)
Pages (from-to)1001-1009
Number of pages9
JournalMayo Clinic proceedings
Volume84
Issue number11
DOIs
StatePublished - Nov 2009

Keywords

  • Cardiac magnetic resonance imaging
  • Dilated cardiomyopathy
  • Endomyocardial biopsy
  • Immunotherapy
  • Myocarditis

ASJC Scopus subject areas

  • Medicine(all)

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    Schultz, J. C., Hilliard, A. A., Cooper, L. T., & Rihal, C. S. (2009). Diagnosis and treatment of viral myocarditis. Mayo Clinic proceedings, 84(11), 1001-1009. https://doi.org/10.4065/84.11.1001