TY - JOUR
T1 - Diagnosis and Management of Microscopic Colitis
AU - Pardi, Darrell S.
N1 - Publisher Copyright:
© 2017 by the American College of Gastroenterology.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Microscopic colitis (MC) is a relatively common cause of chronic watery diarrhea, especially in older persons. Associated symptoms, including abdominal pain and arthralgias, are common. The diagnosis is based upon characteristic histological findings in the presence of diarrhea. The two types of MC, collagenous and lymphocytic colitis, share similar clinical features, with the main difference being the presence or absence of a thickened subepithelial collagen band. There are several treatment options for patients with MC, although only budesonide has been well studied in multiple controlled clinical trials. This review will describe the clinical features, epidemiology, pathophysiology, diagnostic criteria, and treatment of patients with MC.
AB - Microscopic colitis (MC) is a relatively common cause of chronic watery diarrhea, especially in older persons. Associated symptoms, including abdominal pain and arthralgias, are common. The diagnosis is based upon characteristic histological findings in the presence of diarrhea. The two types of MC, collagenous and lymphocytic colitis, share similar clinical features, with the main difference being the presence or absence of a thickened subepithelial collagen band. There are several treatment options for patients with MC, although only budesonide has been well studied in multiple controlled clinical trials. This review will describe the clinical features, epidemiology, pathophysiology, diagnostic criteria, and treatment of patients with MC.
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U2 - 10.1038/ajg.2016.477
DO - 10.1038/ajg.2016.477
M3 - Article
C2 - 27897155
AN - SCOPUS:85000577480
SN - 0002-9270
VL - 112
SP - 78
EP - 85
JO - American Journal of Gastroenterology
JF - American Journal of Gastroenterology
IS - 1
ER -