Diagnosis and management of cerebral venous thrombosis: A statement for healthcare professionals from the American Heart Association/American Stroke Association

Gustavo Saposnik, Fernando Barinagarrementeria, Robert D. Brown, Cheryl D. Bushnell, Brett Cucchiara, Mary Cushman, Gabrielle Deveber, Jose M. Ferro, Fong Y. Tsai

Research output: Contribution to journalArticle

804 Scopus citations

Abstract

Background- The purpose of this statement is to provide an overview of cerebral venous sinus thrombosis and to provide recommendations for its diagnosis, management, and treatment. The intended audience is physicians and other healthcare providers who are responsible for the diagnosis and management of patients with cerebral venous sinus thrombosis. Methods and Results- Members of the panel were appointed by the American Heart Association Stroke Council's Scientific Statement Oversight Committee and represent different areas of expertise. The panel reviewed the relevant literature with an emphasis on reports published since 1966 and used the American Heart Association levels-of-evidence grading algorithm to rate the evidence and to make recommendations. After approval of the statement by the panel, it underwent peer review and approval by the American Heart Association Science Advisory and Coordinating Committee. Conclusions- Evidence-based recommendations are provided for the diagnosis, management, and prevention of recurrence of cerebral venous thrombosis. Recommendations on the evaluation and management of cerebral venous thrombosis during pregnancy and in the pediatric population are provided. Considerations for the management of clinical complications (seizures, hydrocephalus, intracranial hypertension, and neurological deterioration) are also summarized. An algorithm for diagnosis and management of patients with cerebral venous sinus thrombosis is described.

Original languageEnglish (US)
Pages (from-to)1158-1192
Number of pages35
JournalStroke
Volume42
Issue number4
DOIs
StatePublished - Apr 1 2011

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Keywords

  • AHA Scientific Statements
  • anticoagulants
  • brain infarction, venous
  • children
  • disease management
  • outcome assessment
  • pregnancy
  • prognosis
  • sinus thrombosis, intracranial
  • stroke
  • venous thrombosis

ASJC Scopus subject areas

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing

Cite this

Saposnik, G., Barinagarrementeria, F., Brown, R. D., Bushnell, C. D., Cucchiara, B., Cushman, M., Deveber, G., Ferro, J. M., & Tsai, F. Y. (2011). Diagnosis and management of cerebral venous thrombosis: A statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke, 42(4), 1158-1192. https://doi.org/10.1161/STR.0b013e31820a8364