Diagnosis and 10-year follow-up of a community-based hepatitis C cohort

Barbara P. Yawn, Peter Wollan, Liliana Gazzuola, W. Ray Kim

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

OBJECTIVE: To determine the health care follow-up and treatment associated with physician-diagnosed hepatitis C (HCV) in a community-based population. STUDY DESIGN: We conducted a retrospective medical record review using records from all providers in Olmsted County, Minnesota. POPULATION: The study incorporated all Olmsted County residents with physician-diagnosed hepatitis C from 1990 through 1999. OUTCOMES MEASURED: We assessed demographic and health status information as well as health services use in subjects with physician-diagnosed HCV. RESULTS: Physicians diagnosed hepatitis C in 355 subjects (219 men [62%], 136 women [38%]), mean age 43 years, in the 10-year period studied. About half of diagnoses (45%, n = 159) were confirmed with polymerase chain reaction or liver biopsies. Identified risk factors included IV drug use (50%), multiple sex partners (36%), and blood transfusion (30%). Follow-up assessment with aspartate amino-transferase/amino alanine transferase (AST/ALT) tests occurred in about half (49%) of subjects, while 202 subjects (60%) were referred for gastrointestinal (GI) specialist evaluation and 49 patients (14% of all, 25% of those referred to a GI specialist) had specific treatment for hepatitis C. Although well over half of patients (60%) had possible contraindications to HCV treatment, including heavy alcohol use, few were referred for chemical dependency therapy. CONCLUSIONS: In this community, follow-up and treatment related to HCV were limited. Attention to prevention of disease-accelerating co-infections was only modest. Referral or documented recommendations for treatment of alcoholism or heavy chronic alcohol ingestion were minimal.

Original languageEnglish (US)
Pages (from-to)135-140
Number of pages6
JournalJournal of Family Practice
Volume51
Issue number2
StatePublished - 2002
Externally publishedYes

Fingerprint

Hepatitis C
Physicians
Transferases
Therapeutics
Alcohols
Information Services
Sexual Partners
Coinfection
Aspartic Acid
Blood Transfusion
Alanine
Alcoholism
Health Status
Health Services
Medical Records
Referral and Consultation
Eating
Demography
Delivery of Health Care
Biopsy

Keywords

  • Hepatitis C
  • Population based [non-MeSH]
  • Primary health care
  • Secondary prevention [non-MeSH]

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Yawn, B. P., Wollan, P., Gazzuola, L., & Ray Kim, W. (2002). Diagnosis and 10-year follow-up of a community-based hepatitis C cohort. Journal of Family Practice, 51(2), 135-140.

Diagnosis and 10-year follow-up of a community-based hepatitis C cohort. / Yawn, Barbara P.; Wollan, Peter; Gazzuola, Liliana; Ray Kim, W.

In: Journal of Family Practice, Vol. 51, No. 2, 2002, p. 135-140.

Research output: Contribution to journalArticle

Yawn, BP, Wollan, P, Gazzuola, L & Ray Kim, W 2002, 'Diagnosis and 10-year follow-up of a community-based hepatitis C cohort', Journal of Family Practice, vol. 51, no. 2, pp. 135-140.
Yawn BP, Wollan P, Gazzuola L, Ray Kim W. Diagnosis and 10-year follow-up of a community-based hepatitis C cohort. Journal of Family Practice. 2002;51(2):135-140.
Yawn, Barbara P. ; Wollan, Peter ; Gazzuola, Liliana ; Ray Kim, W. / Diagnosis and 10-year follow-up of a community-based hepatitis C cohort. In: Journal of Family Practice. 2002 ; Vol. 51, No. 2. pp. 135-140.
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