Diagnosing Lyme Disease: The Contribution of Serologic Testing

JOSEPH DUFFY, LESTER E. MERTZ, GARY H. WOBIG, JERRY A. KATZMANN

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21 Scopus citations

Abstract

Lyme disease is a multisystem disorder caused by a tick-transmitted spirochete, Borrelia burgdorferi. The diagnosis is based on clinical findings in most patients, particularly those with erythema migrans or exposure to geographic locations endemic for the disease. Detection of a specific antibody to B. burgdorferi is a useful confirmatory test in many patients. In atypical cases, however, a positive test result can be pivotal for determining the diagnosis and can lead to institution of definitive treatment. Serologic testing should not be used indiscriminately to diagnose Lyme disease or as the sole basis for administration of antibiotic therapy.

Original languageEnglish (US)
Pages (from-to)1116-1121
Number of pages6
JournalMayo Clinic proceedings
Volume63
Issue number11
DOIs
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Medicine(all)

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    DUFFY, JOSEPH., MERTZ, LESTER. E., WOBIG, GARY. H., & KATZMANN, JERRY. A. (1988). Diagnosing Lyme Disease: The Contribution of Serologic Testing. Mayo Clinic proceedings, 63(11), 1116-1121. https://doi.org/10.1016/S0025-6196(12)65506-2