Diabetes, pancreatogenic diabetes, and pancreatic cancer

Dana K. Andersen, Murray Korc, Gloria M. Petersen, Guido Eibl, Donghui Li, Michael R. Rickels, Suresh T. Chari, James L. Abbruzzese

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63 Scopus citations

Abstract

The relationships between diabetes and pancreatic ductal adenocarcinoma (PDAC) are complex. Longstanding type 2 diabetes (T2DM) is a risk factor for pancreatic cancer, but increasing epidemiological data point to PDAC as also a cause of diabetes due to unknown mechanisms. New-onset diabetes is of particular interest to the oncology community as the differentiation of new-onset diabetes caused by PDAC as distinct from T2DM may allow for earlier diagnosis of PDAC. To address these relationships and raise awareness of the relationships between PDAC and diabetes, a symposium entitled Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer was held at the American Diabetes Association's 76th Scientific Sessions in June 2016. This article summarizes the data presented at that symposium, describing the current understanding of the interrelationships between diabetes, diabetes management, and pancreatic cancer, and identifies areas where additional research is needed.

Original languageEnglish (US)
Pages (from-to)1103-1110
Number of pages8
JournalDiabetes
Volume66
Issue number5
DOIs
StatePublished - May 1 2017

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ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

Cite this

Andersen, D. K., Korc, M., Petersen, G. M., Eibl, G., Li, D., Rickels, M. R., Chari, S. T., & Abbruzzese, J. L. (2017). Diabetes, pancreatogenic diabetes, and pancreatic cancer. Diabetes, 66(5), 1103-1110. https://doi.org/10.2337/db16-1477