Diabetes

Gwen Lomberk

Research output: Contribution to journalShort survey

2 Citations (Scopus)

Abstract

Pancreatologists have often divided research of the pancreas based upon the origin of the function or disease, namely the endocrine or exocrine pancreas. In fact, as a result, many of our meetings and conferences have followed separate paths. Interestingly, among patients with chronic pancreatitis and pancreatic cancer, both disorders of the exocrine pancreas, diabetes is common. However, the clinical features of the diabetes associated with these two differ. Peripheral insulin resistance and hyperinsulinemia are the predominant diabetic traits in pancreatic cancer, while reduced islet cell mass and impaired insulin secretion are observed more often in chronic pancreatitis. The causal relationship between diabetes and pancreatic cancer remains an intriguing but unanswered question. Since diabetes often precedes pancreatic cancer, it is regarded as a potential risk factor for malignancy. On the other hand, there remains the possibility that pancreatic cancer secretes diabetogenic factors. Regardless of how the science ultimately illuminates this issue, there is increasing interest in utilizing screening for diabetes to aid early detection of pancreatic tumor lesions. Therefore, in this issue of Pancreatology and the Web, we explore the topic of diabetes to keep us alert to this very important association, even if we study diseases of the exocrine pancreas.

Original languageEnglish (US)
Pages (from-to)200-202
Number of pages3
JournalPancreatology
Volume9
Issue number3
DOIs
StatePublished - May 2009

Fingerprint

Pancreatic Neoplasms
Exocrine Pancreas
Chronic Pancreatitis
Islets of Langerhans
Hyperinsulinism
Vascular Resistance
Insulin Resistance
Pancreas
Neoplasms
Insulin
Research

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Hepatology

Cite this

Lomberk, G. (2009). Diabetes. Pancreatology, 9(3), 200-202. https://doi.org/10.1159/000187722

Diabetes. / Lomberk, Gwen.

In: Pancreatology, Vol. 9, No. 3, 05.2009, p. 200-202.

Research output: Contribution to journalShort survey

Lomberk, G 2009, 'Diabetes', Pancreatology, vol. 9, no. 3, pp. 200-202. https://doi.org/10.1159/000187722
Lomberk G. Diabetes. Pancreatology. 2009 May;9(3):200-202. https://doi.org/10.1159/000187722
Lomberk, Gwen. / Diabetes. In: Pancreatology. 2009 ; Vol. 9, No. 3. pp. 200-202.
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