Development of the summary of findings table for network meta-analysis

Juan José Yepes-Nuñez, Shelly Anne Li, Gordon Guyatt, Susan M. Jack, Jan L. Brozek, Joseph Beyene, Mohammad H Murad, Bram Rochwerg, Lawrence Mbuagbaw, Yuan Zhang, Ivan D. Flórez, Reed A. Siemieniuk, Behnam Sadeghirad, Reem Mustafa, Nancy Santesso, Holger J. Schünemann

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Objectives: The aim of the study was to develop a Grading of Recommendations, Assessment, Development and Evaluation (GRADE) summary of findings (SoF) table format that displays the critical information from a network meta-analysis (NMA). Study Design and Setting: We applied a user experience model for data analysis based on four rounds of semistructured interviews. Results: We interviewed 32 stakeholders who conduct or use MA. Four rounds of interviews produced six candidate NMA-SoF tables. Users found a final NMA-SoF table that included the following components highly acceptable: (1) details of the clinical question (PICO), (2) a plot depicting network geometry, (3) relative and absolute effect estimates, (4) certainty of evidence, (5) ranking of treatments, and (6) interpretation of findings. Conclusion: Using stakeholder feedback, we developed a new GRADE NMA-SoF table that includes the relevant components that facilitate understanding NMA findings and health decision-making.

Original languageEnglish (US)
Pages (from-to)1-13
Number of pages13
JournalJournal of Clinical Epidemiology
Volume115
DOIs
StatePublished - Nov 1 2019

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Interviews
Information Services
Decision Making
Network Meta-Analysis
Health

Keywords

  • Certainty of evidence
  • Decision-making
  • GRADE
  • Network meta-analysis
  • Summary of findings
  • Systematic reviews

ASJC Scopus subject areas

  • Epidemiology

Cite this

Yepes-Nuñez, J. J., Li, S. A., Guyatt, G., Jack, S. M., Brozek, J. L., Beyene, J., ... Schünemann, H. J. (2019). Development of the summary of findings table for network meta-analysis. Journal of Clinical Epidemiology, 115, 1-13. https://doi.org/10.1016/j.jclinepi.2019.04.018

Development of the summary of findings table for network meta-analysis. / Yepes-Nuñez, Juan José; Li, Shelly Anne; Guyatt, Gordon; Jack, Susan M.; Brozek, Jan L.; Beyene, Joseph; Murad, Mohammad H; Rochwerg, Bram; Mbuagbaw, Lawrence; Zhang, Yuan; Flórez, Ivan D.; Siemieniuk, Reed A.; Sadeghirad, Behnam; Mustafa, Reem; Santesso, Nancy; Schünemann, Holger J.

In: Journal of Clinical Epidemiology, Vol. 115, 01.11.2019, p. 1-13.

Research output: Contribution to journalArticle

Yepes-Nuñez, JJ, Li, SA, Guyatt, G, Jack, SM, Brozek, JL, Beyene, J, Murad, MH, Rochwerg, B, Mbuagbaw, L, Zhang, Y, Flórez, ID, Siemieniuk, RA, Sadeghirad, B, Mustafa, R, Santesso, N & Schünemann, HJ 2019, 'Development of the summary of findings table for network meta-analysis', Journal of Clinical Epidemiology, vol. 115, pp. 1-13. https://doi.org/10.1016/j.jclinepi.2019.04.018
Yepes-Nuñez, Juan José ; Li, Shelly Anne ; Guyatt, Gordon ; Jack, Susan M. ; Brozek, Jan L. ; Beyene, Joseph ; Murad, Mohammad H ; Rochwerg, Bram ; Mbuagbaw, Lawrence ; Zhang, Yuan ; Flórez, Ivan D. ; Siemieniuk, Reed A. ; Sadeghirad, Behnam ; Mustafa, Reem ; Santesso, Nancy ; Schünemann, Holger J. / Development of the summary of findings table for network meta-analysis. In: Journal of Clinical Epidemiology. 2019 ; Vol. 115. pp. 1-13.
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