TY - JOUR
T1 - Development of a quality improvement learning collaborative to improve pediatric sepsis outcomes
AU - ON BEHALF OF THE IMPROVING PEDIATRIC SEPSIS OUTCOMES COLLABORATIVE INVESTIGATORS
AU - Larsen, Gitte Y.
AU - Brilli, Richard
AU - Macias, Charles G.
AU - Niedner, Matthew
AU - Auletta, Jeffery J.
AU - Balamuth, Fran
AU - Campbell, Deborah
AU - Depinet, Holly
AU - Frizzola, Meg
AU - Hueschen, Leslie
AU - Lowerre, Tracy
AU - Mack, Elizabeth
AU - Paul, Raina
AU - Razzaqi, Faisal
AU - Schafer, Melissa
AU - Scott, Halden F.
AU - Silver, Pete
AU - Wathen, Beth
AU - Lukasiewicz, Gloria
AU - Stuart, Jayne
AU - Riggs, Ruth
AU - Richardson, Troy
AU - Ward, Lowrie
AU - Huskins, W. Charles
N1 - Publisher Copyright:
Copyright © 2021 by the American Academy of Pediatrics
PY - 2021
Y1 - 2021
N2 - Pediatric sepsis is a major public health problem. Published treatment guidelines and several initiatives have increased adherence with guideline recommendations and have improved patient outcomes, but the gains are modest, and persistent gaps remain. The Children's Hospital Association Improving Pediatric Sepsis Outcomes (IPSO) collaborative seeks to improve sepsis outcomes in pediatric emergency departments, ICUs, general care units, and hematology/oncology units. We developed a multicenter quality improvement learning collaborative of US children's hospitals. We reviewed treatment guidelines and literature through 2 in-person meetings and multiple conference calls. We defined and analyzed baseline sepsis-attributable mortality and hospital-onset sepsis and developed a key driver diagram (KDD) on the basis of treatment guidelines, available evidence, and expert opinion. Fifty-six hospital-based teams are participating in IPSO; 100% of teams are engaged in educational and information-sharing activities. A baseline, sepsis-attributable mortality of 3.1% was determined, and the incidence of hospital-onset sepsis was 1.3 cases per 1000 hospital admissions. A KDD was developed with the aim of reducing both the sepsis-attributable mortality and the incidence of hospital-onset sepsis in children by 25% from baseline by December 2020. To accomplish these aims, the KDD primary drivers focus on improving the following: treatment of infection; recognition, diagnosis, and treatment of sepsis; de-escalation of unnecessary care; engagement of patients and families; and methods to optimize performance. IPSO aims to improve sepsis outcomes through collaborative learning and reliable implementation of evidence-based interventions.
AB - Pediatric sepsis is a major public health problem. Published treatment guidelines and several initiatives have increased adherence with guideline recommendations and have improved patient outcomes, but the gains are modest, and persistent gaps remain. The Children's Hospital Association Improving Pediatric Sepsis Outcomes (IPSO) collaborative seeks to improve sepsis outcomes in pediatric emergency departments, ICUs, general care units, and hematology/oncology units. We developed a multicenter quality improvement learning collaborative of US children's hospitals. We reviewed treatment guidelines and literature through 2 in-person meetings and multiple conference calls. We defined and analyzed baseline sepsis-attributable mortality and hospital-onset sepsis and developed a key driver diagram (KDD) on the basis of treatment guidelines, available evidence, and expert opinion. Fifty-six hospital-based teams are participating in IPSO; 100% of teams are engaged in educational and information-sharing activities. A baseline, sepsis-attributable mortality of 3.1% was determined, and the incidence of hospital-onset sepsis was 1.3 cases per 1000 hospital admissions. A KDD was developed with the aim of reducing both the sepsis-attributable mortality and the incidence of hospital-onset sepsis in children by 25% from baseline by December 2020. To accomplish these aims, the KDD primary drivers focus on improving the following: treatment of infection; recognition, diagnosis, and treatment of sepsis; de-escalation of unnecessary care; engagement of patients and families; and methods to optimize performance. IPSO aims to improve sepsis outcomes through collaborative learning and reliable implementation of evidence-based interventions.
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U2 - 10.1542/PEDS.2020-1434
DO - 10.1542/PEDS.2020-1434
M3 - Article
C2 - 33328337
AN - SCOPUS:85099326305
SN - 0031-4005
VL - 147
JO - Pediatrics
JF - Pediatrics
IS - 1
M1 - e20201434
ER -