Development, growth, propagation, and angiographic utilization of the rabbit VX2 model of liver cancer: A pictorial primer and "how to" guide

Ahmad Parvinian, Leigh C. Casadaban, Ron C. Gaba

Research output: Contribution to journalArticlepeer-review

46 Scopus citations

Abstract

The VX2 tumor is a leporine anaplastic squamous cell carcinoma characterized by rapid growth, hypervascularity, and facile propagation in the skeletal muscle. Since its introduction over 70 years ago, it has been used to model a variety of malignancies, and is commonly employed by interventional radiologists in preclinical investigations of hepatocellular carcinoma. However, despite the widespread and lasting popularity of the model, there are few technical resources detailing its use. Herein, we present a comprehensive pictorial outline of the technical methodology for development, growth, propagation, and angiographic utilization of the rabbit VX2 liver tumor model.

Original languageEnglish (US)
Pages (from-to)335-340
Number of pages6
JournalDiagnostic and Interventional Radiology
Volume20
Issue number4
DOIs
StatePublished - 2014

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Development, growth, propagation, and angiographic utilization of the rabbit VX2 model of liver cancer: A pictorial primer and "how to" guide'. Together they form a unique fingerprint.

Cite this