Developing patient-specific anatomic models for validation of cardiac ablation guidance procedures

David R. Holmes III, Maryam Rettmann, Bruce Cameron, Jon Camp, Richard Robb

Research output: Chapter in Book/Report/Conference proceedingConference contribution

9 Citations (Scopus)

Abstract

Image-guided cardiac ablation has the potential to decrease procedure times and improve clinical outcome for patients with cardiac arrhythmias. There are several proposed methods for integrating patient-specific anatomy into the cardiac ablation procedure; however, these methods require thorough validation. One of the primary challenges in validation is determining ground truth as a standard for comparison. Some validation protocols have been developed for animals models and even in patients; however, these methods can be costly to implement and may increase the risk to patients. We have developed an approach to building realistic patient-specific anatomic models at a low-cost in order to validate the guidance procedure without introducing additional risk to the patients. Using a pre-procedural cardiac computed tomography scan, the blood pool of the left and right atria of a patient are segmented semi-manually. In addition, several anatomical landmarks are identified in the image data. The segmented atria and landmarks are converted into a polygonalized model which is used to build a thin-walled patient-specific blood pool model in a stereo-lithography system. Thumbscrews are inserted into the model at the landmarks. The entire model is embedded in a platinum silicone material which has been shown to have tissue-mimicking properties relative to ultrasound. Once the pliable mold has set, the blood pool model is extracted by dissolving the rigid material. The resulting physical model correctly mimics a specific patient anatomy with embedded fiducals which can be used for validation experiments. The patient-specific anatomic model approach may also be used for pre-surgical practice and training of new interventionalists.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6918
DOIs
StatePublished - 2008
EventMedical Imaging 2008 - Visualization, Image-Guided Procedures, and Modeling - San Diego, CA, United States
Duration: Feb 17 2008Feb 19 2008

Other

OtherMedical Imaging 2008 - Visualization, Image-Guided Procedures, and Modeling
CountryUnited States
CitySan Diego, CA
Period2/17/082/19/08

Fingerprint

Ablation
Blood
Silicones
Lithography
Tomography
Platinum
Animals
Ultrasonics
Tissue

Keywords

  • Cardiac Procedures
  • Surgical Simulation
  • Validation

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Holmes III, D. R., Rettmann, M., Cameron, B., Camp, J., & Robb, R. (2008). Developing patient-specific anatomic models for validation of cardiac ablation guidance procedures. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 6918). [69181W] https://doi.org/10.1117/12.773215

Developing patient-specific anatomic models for validation of cardiac ablation guidance procedures. / Holmes III, David R.; Rettmann, Maryam; Cameron, Bruce; Camp, Jon; Robb, Richard.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6918 2008. 69181W.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Holmes III, DR, Rettmann, M, Cameron, B, Camp, J & Robb, R 2008, Developing patient-specific anatomic models for validation of cardiac ablation guidance procedures. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 6918, 69181W, Medical Imaging 2008 - Visualization, Image-Guided Procedures, and Modeling, San Diego, CA, United States, 2/17/08. https://doi.org/10.1117/12.773215
Holmes III DR, Rettmann M, Cameron B, Camp J, Robb R. Developing patient-specific anatomic models for validation of cardiac ablation guidance procedures. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6918. 2008. 69181W https://doi.org/10.1117/12.773215
Holmes III, David R. ; Rettmann, Maryam ; Cameron, Bruce ; Camp, Jon ; Robb, Richard. / Developing patient-specific anatomic models for validation of cardiac ablation guidance procedures. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6918 2008.
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