Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010

Zaven S. Khachaturian; Ronald C. Petersen; Peter J. Snyder; Ara S. Khachaturian; Paul Aisen; Mony De Leon; Barry D. Greenberg; Walter Kukull; Paul Maruff; Reisa A. Sperling; Yaakov Stern; Jacques Touchon; Bruno Vellas; Sandrine Andrieu; Michael W. Weiner; Maria C. Carrillo; Lisa J. Bain

doi:10.1016/j.jalz.2011.02.005

Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010

Zaven S. Khachaturian, Ronald C. Petersen, Peter J. Snyder, Ara S. Khachaturian, Paul Aisen, Mony De Leon, Barry D. Greenberg, Walter Kukull, Paul Maruff, Reisa A. Sperling, Yaakov Stern, Jacques Touchon, Bruno Vellas, Sandrine Andrieu, Michael W. Weiner, Maria C. Carrillo, Lisa J. Bain

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Abstract

The fourth Leon Thal Symposium (LTS2010) was convened in Toulouse, France, on November 3, 2010. This symposium reviewed design parameters that are necessary to develop comprehensive national databases on healthy aging. Such datasets offer the potential to serve as the foundation for a systems-approach to solve the dual public health problems of: (1) early detection of people who are at elevated risk for Alzheimer's disease, and (2) the development of interventions to delay onset of, or prevent, late-life dementia. The symposium considered three interrelated components of a National Database for Longitudinal Studies on Healthy Aging as follows: (a) a registry of healthy aging adults; (b) refined computer-based assessments for data gathering, including assessments of behavioral/memory changes associated with aging that are appropriate for broad use in nonexpert settings; and (c) high performance computing/ supercomputer-based approaches for health data modeling and mining.

Original language	English (US)
Pages (from-to)	127-132
Number of pages	6
Journal	Alzheimer's and Dementia
Volume	7
Issue number	2
DOIs	https://doi.org/10.1016/j.jalz.2011.02.005
State	Published - Mar 2011

Keywords

Alzheimer's disease
Biomarkers
Computational biology
Computerized cognitive assessment
Dementia
Genetics
Healthy aging
In silico modeling
Longitudinal study
Mild cognitive impairment
Presymptomatic Alzheimer's disease
Prevention
Registry

ASJC Scopus subject areas

Epidemiology
Health Policy
Developmental Neuroscience
Clinical Neurology
Geriatrics and Gerontology
Cellular and Molecular Neuroscience
Psychiatry and Mental health

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10.1016/j.jalz.2011.02.005

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Khachaturian, Z. S., Petersen, R. C., Snyder, P. J., Khachaturian, A. S., Aisen, P., De Leon, M., Greenberg, B. D., Kukull, W., Maruff, P., Sperling, R. A., Stern, Y., Touchon, J., Vellas, B., Andrieu, S., Weiner, M. W., Carrillo, M. C., & Bain, L. J. (2011). Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010. Alzheimer's and Dementia, 7(2), 127-132. https://doi.org/10.1016/j.jalz.2011.02.005

Khachaturian, ZS, Petersen, RC, Snyder, PJ, Khachaturian, AS, Aisen, P, De Leon, M, Greenberg, BD, Kukull, W, Maruff, P, Sperling, RA, Stern, Y, Touchon, J, Vellas, B, Andrieu, S, Weiner, MW, Carrillo, MC & Bain, LJ 2011, 'Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010', Alzheimer's and Dementia, vol. 7, no. 2, pp. 127-132. https://doi.org/10.1016/j.jalz.2011.02.005

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abstract = "The fourth Leon Thal Symposium (LTS2010) was convened in Toulouse, France, on November 3, 2010. This symposium reviewed design parameters that are necessary to develop comprehensive national databases on healthy aging. Such datasets offer the potential to serve as the foundation for a systems-approach to solve the dual public health problems of: (1) early detection of people who are at elevated risk for Alzheimer's disease, and (2) the development of interventions to delay onset of, or prevent, late-life dementia. The symposium considered three interrelated components of a National Database for Longitudinal Studies on Healthy Aging as follows: (a) a registry of healthy aging adults; (b) refined computer-based assessments for data gathering, including assessments of behavioral/memory changes associated with aging that are appropriate for broad use in nonexpert settings; and (c) high performance computing/ supercomputer-based approaches for health data modeling and mining.",

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Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010

Abstract

Keywords

ASJC Scopus subject areas

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