Detection of mild coronary stenoses using the Dynamic Spatial Reconstructor

W. J Y Spyra, M. R. Bell, R. C. Bahn, A. R. Zinsmeister, E. L. Ritman, A. A. Bove

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The accuracy of the Dynamic Spatial Reconstructor (DSR) in the detection of moderate coronary artery stenoses was examined in 20 closed-chest dogs. Twenty-eight hollow plastic cylinders were embolized into the left coronary arteries and produced 25% to 56% reductions in arterial lumina diameter. For each dog, one three-dimensional (3-D) image of the heart was reconstructed from each DSR scan recorded during injection of contrast into the aortic root. Analysis involved blinded visual analysis by four independent observers of multiview projection images computed from the single 3-D image. Postmortem coronary angiograms of the isolated heart were considered definitive for location of the stenoses. Overall sensitivity of detection by DSR was 89% and specificity 81%. Sensitivity of detecting stenoses ≥50% was 98%. Receiver operating characteristics (ROC) analysis showed that detection of stenoses in the left coronary arteries is of equal sensitivity and specificity.

Original languageEnglish (US)
Pages (from-to)472-479
Number of pages8
JournalInvestigative Radiology
Volume25
Issue number5
StatePublished - 1990

Fingerprint

Coronary Stenosis
Pathologic Constriction
Three-Dimensional Imaging
Coronary Vessels
Dogs
ROC Curve
Plastics
Angiography
Thorax
Sensitivity and Specificity
Injections

Keywords

  • Angiography
  • Observer performance
  • Receiver operating characteristics
  • Three-dimensional images

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Spyra, W. J. Y., Bell, M. R., Bahn, R. C., Zinsmeister, A. R., Ritman, E. L., & Bove, A. A. (1990). Detection of mild coronary stenoses using the Dynamic Spatial Reconstructor. Investigative Radiology, 25(5), 472-479.

Detection of mild coronary stenoses using the Dynamic Spatial Reconstructor. / Spyra, W. J Y; Bell, M. R.; Bahn, R. C.; Zinsmeister, A. R.; Ritman, E. L.; Bove, A. A.

In: Investigative Radiology, Vol. 25, No. 5, 1990, p. 472-479.

Research output: Contribution to journalArticle

Spyra, WJY, Bell, MR, Bahn, RC, Zinsmeister, AR, Ritman, EL & Bove, AA 1990, 'Detection of mild coronary stenoses using the Dynamic Spatial Reconstructor', Investigative Radiology, vol. 25, no. 5, pp. 472-479.
Spyra WJY, Bell MR, Bahn RC, Zinsmeister AR, Ritman EL, Bove AA. Detection of mild coronary stenoses using the Dynamic Spatial Reconstructor. Investigative Radiology. 1990;25(5):472-479.
Spyra, W. J Y ; Bell, M. R. ; Bahn, R. C. ; Zinsmeister, A. R. ; Ritman, E. L. ; Bove, A. A. / Detection of mild coronary stenoses using the Dynamic Spatial Reconstructor. In: Investigative Radiology. 1990 ; Vol. 25, No. 5. pp. 472-479.
@article{cc009104869c47e398f713e943d41065,
title = "Detection of mild coronary stenoses using the Dynamic Spatial Reconstructor",
abstract = "The accuracy of the Dynamic Spatial Reconstructor (DSR) in the detection of moderate coronary artery stenoses was examined in 20 closed-chest dogs. Twenty-eight hollow plastic cylinders were embolized into the left coronary arteries and produced 25{\%} to 56{\%} reductions in arterial lumina diameter. For each dog, one three-dimensional (3-D) image of the heart was reconstructed from each DSR scan recorded during injection of contrast into the aortic root. Analysis involved blinded visual analysis by four independent observers of multiview projection images computed from the single 3-D image. Postmortem coronary angiograms of the isolated heart were considered definitive for location of the stenoses. Overall sensitivity of detection by DSR was 89{\%} and specificity 81{\%}. Sensitivity of detecting stenoses ≥50{\%} was 98{\%}. Receiver operating characteristics (ROC) analysis showed that detection of stenoses in the left coronary arteries is of equal sensitivity and specificity.",
keywords = "Angiography, Observer performance, Receiver operating characteristics, Three-dimensional images",
author = "Spyra, {W. J Y} and Bell, {M. R.} and Bahn, {R. C.} and Zinsmeister, {A. R.} and Ritman, {E. L.} and Bove, {A. A.}",
year = "1990",
language = "English (US)",
volume = "25",
pages = "472--479",
journal = "Investigative Radiology",
issn = "0020-9996",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

TY - JOUR

T1 - Detection of mild coronary stenoses using the Dynamic Spatial Reconstructor

AU - Spyra, W. J Y

AU - Bell, M. R.

AU - Bahn, R. C.

AU - Zinsmeister, A. R.

AU - Ritman, E. L.

AU - Bove, A. A.

PY - 1990

Y1 - 1990

N2 - The accuracy of the Dynamic Spatial Reconstructor (DSR) in the detection of moderate coronary artery stenoses was examined in 20 closed-chest dogs. Twenty-eight hollow plastic cylinders were embolized into the left coronary arteries and produced 25% to 56% reductions in arterial lumina diameter. For each dog, one three-dimensional (3-D) image of the heart was reconstructed from each DSR scan recorded during injection of contrast into the aortic root. Analysis involved blinded visual analysis by four independent observers of multiview projection images computed from the single 3-D image. Postmortem coronary angiograms of the isolated heart were considered definitive for location of the stenoses. Overall sensitivity of detection by DSR was 89% and specificity 81%. Sensitivity of detecting stenoses ≥50% was 98%. Receiver operating characteristics (ROC) analysis showed that detection of stenoses in the left coronary arteries is of equal sensitivity and specificity.

AB - The accuracy of the Dynamic Spatial Reconstructor (DSR) in the detection of moderate coronary artery stenoses was examined in 20 closed-chest dogs. Twenty-eight hollow plastic cylinders were embolized into the left coronary arteries and produced 25% to 56% reductions in arterial lumina diameter. For each dog, one three-dimensional (3-D) image of the heart was reconstructed from each DSR scan recorded during injection of contrast into the aortic root. Analysis involved blinded visual analysis by four independent observers of multiview projection images computed from the single 3-D image. Postmortem coronary angiograms of the isolated heart were considered definitive for location of the stenoses. Overall sensitivity of detection by DSR was 89% and specificity 81%. Sensitivity of detecting stenoses ≥50% was 98%. Receiver operating characteristics (ROC) analysis showed that detection of stenoses in the left coronary arteries is of equal sensitivity and specificity.

KW - Angiography

KW - Observer performance

KW - Receiver operating characteristics

KW - Three-dimensional images

UR - http://www.scopus.com/inward/record.url?scp=0025340860&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025340860&partnerID=8YFLogxK

M3 - Article

C2 - 2345076

AN - SCOPUS:0025340860

VL - 25

SP - 472

EP - 479

JO - Investigative Radiology

JF - Investigative Radiology

SN - 0020-9996

IS - 5

ER -