Detection of JC virus by polymerase chain reaction in cerebrospinal fluid from two patients with progressive multifocal leukoencephalopathy

A. Telenti; W. F. Marshall; A. J. Aksamit; J. D. Smilack; T. F. Smith

doi:10.1007/BF02098091

Detection of JC virus by polymerase chain reaction in cerebrospinal fluid from two patients with progressive multifocal leukoencephalopathy

A. Telenti, W. F. Marshall, A. J. Aksamit, J. D. Smilack, T. F. Smith

Neurology

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26 Scopus citations

Abstract

The polymerase chain reaction (PCR) was used to identify JC virus (JCV) in the cerebrospinal fluid of two patients with progressive multifocal leukoencephalopathy confirmed by brain biopsy. In addition, JCV viremia was demonstrated by PCR in one case. JCV detection in spinal fluid by PCR may be the first non-invasive technique available for the diagnostic confirmation of progressive multifocal leukoencephalopathy.

Original language	English (US)
Pages (from-to)	253-254
Number of pages	2
Journal	European Journal of Clinical Microbiology & Infectious Diseases
Volume	11
Issue number	3
DOIs	https://doi.org/10.1007/BF02098091
State	Published - Mar 1992

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1007/BF02098091

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abstract = "The polymerase chain reaction (PCR) was used to identify JC virus (JCV) in the cerebrospinal fluid of two patients with progressive multifocal leukoencephalopathy confirmed by brain biopsy. In addition, JCV viremia was demonstrated by PCR in one case. JCV detection in spinal fluid by PCR may be the first non-invasive technique available for the diagnostic confirmation of progressive multifocal leukoencephalopathy.",

author = "A. Telenti and Marshall, {W. F.} and Aksamit, {A. J.} and Smilack, {J. D.} and Smith, {T. F.}",

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AU - Smilack, J. D.

AU - Smith, T. F.

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Detection of JC virus by polymerase chain reaction in cerebrospinal fluid from two patients with progressive multifocal leukoencephalopathy

Abstract

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