Detection of calcium deposits on heart valve leaflets by vibro-acoustography: An in vitro study

Azra Alizad, Mostafa Fatemi, Rick A. Nishimura, Randall R. Kinnick, Edmond Rambod, James F. Greenleaf

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

The presence of calcium deposits on heart valve leaflets constitutes a clinically significant diagnostic indication. A novel method for imaging and detecting calcium deposits on tissue heart valves is presented. The method, called vibro-acoustography, uses the radiation force of ultrasound to vibrate the tissue at low (kHz) frequency and records the resulting acoustic response to produce images that are related to the hardness of the tissue. The method is tested on excised human heart valve tissues. Resulting images clearly show calcium deposits with high contrast and are in agreement with the corresponding radiographs of the specimens.

Original languageEnglish (US)
Pages (from-to)1391-1395
Number of pages5
JournalJournal of the American Society of Echocardiography
Volume15
Issue number11
DOIs
StatePublished - Nov 1 2002

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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