Detection of bowel inflammation with fused DWI/T2 images versus contrast-enhanced images in pediatric MR enterography with histopathologic correlation

Eric Ehman, Andrew S. Phelps, Michael A. Ohliger, Sue J. Rhee, John D. MacKenzie, Jesse L. Courtier

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Purpose To evaluate the fused, colorized diffusion weighted imaging (DWI) and anatomic T2 images compared to routine contrast-enhanced T1 images at pediatric magnetic resonance enterography (MRE). Methods Fused, colorized DWI/T2 images were created from patients with magnetic resonance enterography (MRE) and colonoscopy/biopsy. Radiologists noted inflammation in five bowel segments (terminal ileum–rectosigmoid colon) on postcontrast images and DWI/T2 images. Test characteristics and agreement were calculated. Results For 20 patients, sensitivity/specificity/positive predictive value (PPV)/negative predictive value (NPV) were 0.53/0.90/0.77/0.76 for DWI/T2 and 0.45/0.90/0.72/0.73 for postcontrast images. Intraobserver agreement was ҡ=0.45–0.73. Interobserver agreement was ҡ=0.53 for DWI/T2 and ҡ=0.63 for postcontrast images. Conclusion DWI/T2 images are similar in sensitivity/specificity to contrast-enhanced images and with moderate intra/interobserver reliability.

Original languageEnglish (US)
Pages (from-to)1135-1139
Number of pages5
JournalClinical Imaging
Volume40
Issue number6
DOIs
StatePublished - Nov 1 2016
Externally publishedYes

Keywords

  • Diffusion-weighted imaging
  • Enterography
  • MRI
  • Pediatric

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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