Detection and sequence analysis of hepatitis B virus integration in peripheral blood mononuclear cells

Tomasz Laskus, Marek Radkowski, Lian Fu Wang, Marek Nowicki, Jorge Rakela

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

A PCR-based technique was used to detect hepatitis B virus (HBV) integration in peripheral blood mononuclear cells from patients with chronic hepatitis B. Integrated HBV DNA sequences, with virus-cell junctions located in the cohesive region between direct repeat 1 (DR1) and DR2, were found in 2 of 10 studied patients.

Original languageEnglish (US)
Pages (from-to)1235-1238
Number of pages4
JournalJournal of virology
Volume73
Issue number2
DOIs
StatePublished - 1999

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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