Detection and prognostic impact of micrometastasis in colorectal cancer

Saad Sirop; Mohammed Kanaan; Alpesh Korant; David Wiese; David Eilender; Sunil Nagpal; Madan Arora; Trevor Singh; Sukamal Saha

doi:10.1002/jso.21793

Detection and prognostic impact of micrometastasis in colorectal cancer

Saad Sirop, Mohammed Kanaan, Alpesh Korant, David Wiese, David Eilender, Sunil Nagpal, Madan Arora, Trevor Singh, Sukamal Saha

Hematology

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Review of literature was performed on studies with prognostic impact of micrometastasis in colorectal cancer. Among 16 studies included, micrometastasis was detected in 26.5% of patients. Most analysis revealed that micrometastasis carries a poorer prognosis compared to node negative disease (NND). The results of those studies were compared with our pilot study of 109 patients with colon cancer, showing improved prognosis of micrometastasis after being upstaged and treated with chemotherapy when compared with NND.

Original language	English (US)
Pages (from-to)	534-537
Number of pages	4
Journal	Journal of Surgical Oncology
Volume	103
Issue number	6
DOIs	https://doi.org/10.1002/jso.21793
State	Published - May 1 2011

Keywords

colon
micrometastasis
rectum
sentinel lymph node

ASJC Scopus subject areas

Surgery
Oncology

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10.1002/jso.21793

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title = "Detection and prognostic impact of micrometastasis in colorectal cancer",

abstract = "Review of literature was performed on studies with prognostic impact of micrometastasis in colorectal cancer. Among 16 studies included, micrometastasis was detected in 26.5% of patients. Most analysis revealed that micrometastasis carries a poorer prognosis compared to node negative disease (NND). The results of those studies were compared with our pilot study of 109 patients with colon cancer, showing improved prognosis of micrometastasis after being upstaged and treated with chemotherapy when compared with NND.",

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AU - Sirop, Saad

AU - Kanaan, Mohammed

AU - Korant, Alpesh

AU - Wiese, David

AU - Eilender, David

AU - Nagpal, Sunil

AU - Arora, Madan

AU - Singh, Trevor

AU - Saha, Sukamal

PY - 2011/5/1

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N2 - Review of literature was performed on studies with prognostic impact of micrometastasis in colorectal cancer. Among 16 studies included, micrometastasis was detected in 26.5% of patients. Most analysis revealed that micrometastasis carries a poorer prognosis compared to node negative disease (NND). The results of those studies were compared with our pilot study of 109 patients with colon cancer, showing improved prognosis of micrometastasis after being upstaged and treated with chemotherapy when compared with NND.

AB - Review of literature was performed on studies with prognostic impact of micrometastasis in colorectal cancer. Among 16 studies included, micrometastasis was detected in 26.5% of patients. Most analysis revealed that micrometastasis carries a poorer prognosis compared to node negative disease (NND). The results of those studies were compared with our pilot study of 109 patients with colon cancer, showing improved prognosis of micrometastasis after being upstaged and treated with chemotherapy when compared with NND.

KW - colon

KW - micrometastasis

KW - rectum

KW - sentinel lymph node

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Detection and prognostic impact of micrometastasis in colorectal cancer

Abstract

Keywords

ASJC Scopus subject areas

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