Detection and analysis of hepatitis C virus sequences in cerebrospinal fluid

Tomasz Laskus, Marek Radkowski, Agnieszka Bednarska, Jeffrey Wilkinson, Debra Adair, Marek Nowicki, Georgia B. Nikolopoulou, Hugo Vargas, Jorge Rakela

Research output: Contribution to journalArticle

131 Scopus citations

Abstract

Hepatitis C virus (HCV) sequences were detected in cerebrospinal fluid (CSF) in 8 of 13 HCV-positive patients. In four patients harboring different virus strains in serum and peripheral blood mononuclear cells (PBMC), CSF-derived virus was similar to that found in PBMC, which suggests that PBMC could carry HCV into the brain.

Original languageEnglish (US)
Pages (from-to)10064-10068
Number of pages5
JournalJournal of virology
Volume76
Issue number19
DOIs
StatePublished - Oct 2002

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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  • Cite this

    Laskus, T., Radkowski, M., Bednarska, A., Wilkinson, J., Adair, D., Nowicki, M., Nikolopoulou, G. B., Vargas, H., & Rakela, J. (2002). Detection and analysis of hepatitis C virus sequences in cerebrospinal fluid. Journal of virology, 76(19), 10064-10068. https://doi.org/10.1128/JVI.76.19.10064-10068.2002