Detection and analysis of hepatitis C virus sequences in cerebrospinal fluid

Tomasz Laskus, Marek Radkowski, Agnieszka Bednarska, Jeffrey Wilkinson, Debra Adair, Marek Nowicki, Georgia B. Nikolopoulou, Hugo E Vargas, Jorge Rakela

Research output: Contribution to journalArticle

131 Citations (Scopus)

Abstract

Hepatitis C virus (HCV) sequences were detected in cerebrospinal fluid (CSF) in 8 of 13 HCV-positive patients. In four patients harboring different virus strains in serum and peripheral blood mononuclear cells (PBMC), CSF-derived virus was similar to that found in PBMC, which suggests that PBMC could carry HCV into the brain.

Original languageEnglish (US)
Pages (from-to)10064-10068
Number of pages5
JournalJournal of Virology
Volume76
Issue number19
DOIs
StatePublished - Oct 2002

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Hepatitis C virus
cerebrospinal fluid
mononuclear leukocytes
Hepacivirus
Cerebrospinal Fluid
Blood Cells
Viruses
viruses
brain
Brain
Serum

ASJC Scopus subject areas

  • Immunology

Cite this

Laskus, T., Radkowski, M., Bednarska, A., Wilkinson, J., Adair, D., Nowicki, M., ... Rakela, J. (2002). Detection and analysis of hepatitis C virus sequences in cerebrospinal fluid. Journal of Virology, 76(19), 10064-10068. https://doi.org/10.1128/JVI.76.19.10064-10068.2002

Detection and analysis of hepatitis C virus sequences in cerebrospinal fluid. / Laskus, Tomasz; Radkowski, Marek; Bednarska, Agnieszka; Wilkinson, Jeffrey; Adair, Debra; Nowicki, Marek; Nikolopoulou, Georgia B.; Vargas, Hugo E; Rakela, Jorge.

In: Journal of Virology, Vol. 76, No. 19, 10.2002, p. 10064-10068.

Research output: Contribution to journalArticle

Laskus, T, Radkowski, M, Bednarska, A, Wilkinson, J, Adair, D, Nowicki, M, Nikolopoulou, GB, Vargas, HE & Rakela, J 2002, 'Detection and analysis of hepatitis C virus sequences in cerebrospinal fluid', Journal of Virology, vol. 76, no. 19, pp. 10064-10068. https://doi.org/10.1128/JVI.76.19.10064-10068.2002
Laskus T, Radkowski M, Bednarska A, Wilkinson J, Adair D, Nowicki M et al. Detection and analysis of hepatitis C virus sequences in cerebrospinal fluid. Journal of Virology. 2002 Oct;76(19):10064-10068. https://doi.org/10.1128/JVI.76.19.10064-10068.2002
Laskus, Tomasz ; Radkowski, Marek ; Bednarska, Agnieszka ; Wilkinson, Jeffrey ; Adair, Debra ; Nowicki, Marek ; Nikolopoulou, Georgia B. ; Vargas, Hugo E ; Rakela, Jorge. / Detection and analysis of hepatitis C virus sequences in cerebrospinal fluid. In: Journal of Virology. 2002 ; Vol. 76, No. 19. pp. 10064-10068.
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