Detecting fabrication of data in a multicenter collaborative animal study

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

In 1980-1981 the National Heart, Lung, and Blood Institute (NHLBI) sponsored a multicenter study of animal models for protection of ischemic myocardium (AMPIM). After data collection for the study was complete, problems were identified with data from one of the labs. This article deals with the issue of statistical evidence versus hard evidence as well as the process of crossing the boundary from suspicion to certainty regarding the nature and extent of the problem.

Original languageEnglish (US)
Pages (from-to)741-752
Number of pages12
JournalControlled Clinical Trials
Volume12
Issue number6
DOIs
StatePublished - 1991

Fingerprint

National Heart, Lung, and Blood Institute (U.S.)
Multicenter Studies
Myocardium
Animal Models

Keywords

  • collaborative research
  • Evidence
  • fraud
  • lack of variation

ASJC Scopus subject areas

  • Pharmacology

Cite this

Detecting fabrication of data in a multicenter collaborative animal study. / Bailey, Kent R.

In: Controlled Clinical Trials, Vol. 12, No. 6, 1991, p. 741-752.

Research output: Contribution to journalArticle

@article{833f63c673114736a11d9e01074b2aca,
title = "Detecting fabrication of data in a multicenter collaborative animal study",
abstract = "In 1980-1981 the National Heart, Lung, and Blood Institute (NHLBI) sponsored a multicenter study of animal models for protection of ischemic myocardium (AMPIM). After data collection for the study was complete, problems were identified with data from one of the labs. This article deals with the issue of statistical evidence versus hard evidence as well as the process of crossing the boundary from suspicion to certainty regarding the nature and extent of the problem.",
keywords = "collaborative research, Evidence, fraud, lack of variation",
author = "Bailey, {Kent R}",
year = "1991",
doi = "10.1016/0197-2456(91)90037-M",
language = "English (US)",
volume = "12",
pages = "741--752",
journal = "Controlled Clinical Trials",
issn = "0197-2456",
publisher = "Elsevier BV",
number = "6",

}

TY - JOUR

T1 - Detecting fabrication of data in a multicenter collaborative animal study

AU - Bailey, Kent R

PY - 1991

Y1 - 1991

N2 - In 1980-1981 the National Heart, Lung, and Blood Institute (NHLBI) sponsored a multicenter study of animal models for protection of ischemic myocardium (AMPIM). After data collection for the study was complete, problems were identified with data from one of the labs. This article deals with the issue of statistical evidence versus hard evidence as well as the process of crossing the boundary from suspicion to certainty regarding the nature and extent of the problem.

AB - In 1980-1981 the National Heart, Lung, and Blood Institute (NHLBI) sponsored a multicenter study of animal models for protection of ischemic myocardium (AMPIM). After data collection for the study was complete, problems were identified with data from one of the labs. This article deals with the issue of statistical evidence versus hard evidence as well as the process of crossing the boundary from suspicion to certainty regarding the nature and extent of the problem.

KW - collaborative research

KW - Evidence

KW - fraud

KW - lack of variation

UR - http://www.scopus.com/inward/record.url?scp=0026330988&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026330988&partnerID=8YFLogxK

U2 - 10.1016/0197-2456(91)90037-M

DO - 10.1016/0197-2456(91)90037-M

M3 - Article

VL - 12

SP - 741

EP - 752

JO - Controlled Clinical Trials

JF - Controlled Clinical Trials

SN - 0197-2456

IS - 6

ER -