Desquamative interstitial pneumonia: Thin-section CT findings in 22 patients

T. E. Hartman, S. L. Primack, S. J. Swensen, D. Hansell, G. McGuinness, N. L. Muller

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185 Scopus citations


To evaluate the findings on thin-section computed tomographic (CT) scans in desquamative interstitial pneumonia (DIP), the CT scans from 22 patients aged 22-71 years (mean age, 43 years) were reviewed. In all patients, DIP was proved with open-lung biopsy performed 1 day to 17 months before or after examination with CT (median interval, 1.5 months). The lungs were divided into three zones (upper, middle, and lower); each zone was evaluated separately. The predominant finding was the presence of areas of ground- glass attenuation that involved the middle and lower lung zones in all patients and the upper lung zones in 18 patients (82%). Such areas had a lower lung zone predominance in 16 patients (73%) and a predominantly peripheral distribution in 13 patients (59%). Irregular lines of attenuation suggestive of fibrosis were seen in 11 patients (50%) and cystic changes, in seven patients (32%). The distribution of abnormalities in DIP is similar to that seen in usual interstitial pneumonia (UIP), but the greater extent of ground-glass attenuation and the paucity of cystic changes in DIP should enable distinction from UIP in most patients.

Original languageEnglish (US)
Pages (from-to)787-790
Number of pages4
Issue number3
StatePublished - Jan 1 1993


  • Computed tomography (CT), thin-section
  • Lung, fibrosis
  • Pneumonitis, desquamative interstitial

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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