Designer natriuretic peptides

Candace Y W Lee, Hsiao Lieu, John C Jr. Burnett

Research output: Contribution to journalArticle

Abstract

Designer natriuretic peptides (NPs) are novel hybrid peptides that are engineered from the native NPs through addition, deletion, or substitution of amino acid(s) with a goal toward optimization of pharmacological actions while minimizing undesirable effects. In this article, selected peptides that were designed in our laboratory are reviewed, and future directions for research and development of designer NPs are discussed.

Original languageEnglish (US)
Pages (from-to)18-21
Number of pages4
JournalJournal of Investigative Medicine
Volume57
Issue number1
DOIs
StatePublished - Jan 2009

Fingerprint

Natriuretic Peptides
Peptides
Amino Acid Substitution
Substitution reactions
Pharmacology
Amino Acids
Research

Keywords

  • Hybrid peptides
  • Natriuretic peptide
  • Renal function

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Designer natriuretic peptides. / Lee, Candace Y W; Lieu, Hsiao; Burnett, John C Jr.

In: Journal of Investigative Medicine, Vol. 57, No. 1, 01.2009, p. 18-21.

Research output: Contribution to journalArticle

Lee, Candace Y W ; Lieu, Hsiao ; Burnett, John C Jr. / Designer natriuretic peptides. In: Journal of Investigative Medicine. 2009 ; Vol. 57, No. 1. pp. 18-21.
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