Design and synthesis of novel pegylated 4-methylcoumarins

Mukesh Pandey, Rahul Tyagi, Shilpi Tomar, Jayant Kumar, Virinder S. Parmar, Arthur C. Watterson

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Coumarins are well known for their antioxidant and anti-edema activities. Their antioxidant property gets enhanced with a methyl group at the C-4 position of the pyran ring. To increase the antioxidant potential and their hydrophilicity, a lipase (Novozyme 435) catalyzed copolymerization of 4-methylcoumarin diesters and polyethylene glycols (PEGs) has been carried out to give novel copolymers.

Original languageEnglish (US)
Pages (from-to)1293-1298
Number of pages6
JournalJournal of Macromolecular Science, Part A: Pure and Applied Chemistry
Volume44
Issue number12
DOIs
StatePublished - Dec 1 2007
Externally publishedYes

Fingerprint

Antioxidants
Pyrans
Coumarins
Lipases
Hydrophilicity
Lipase
Copolymerization
Polyethylene glycols
Copolymers

Keywords

  • 4-methylcoumarin
  • Antioxidant
  • Lipase
  • PEG

ASJC Scopus subject areas

  • Ceramics and Composites
  • Chemistry(all)
  • Polymers and Plastics
  • Materials Chemistry

Cite this

Design and synthesis of novel pegylated 4-methylcoumarins. / Pandey, Mukesh; Tyagi, Rahul; Tomar, Shilpi; Kumar, Jayant; Parmar, Virinder S.; Watterson, Arthur C.

In: Journal of Macromolecular Science, Part A: Pure and Applied Chemistry, Vol. 44, No. 12, 01.12.2007, p. 1293-1298.

Research output: Contribution to journalArticle

Pandey, Mukesh ; Tyagi, Rahul ; Tomar, Shilpi ; Kumar, Jayant ; Parmar, Virinder S. ; Watterson, Arthur C. / Design and synthesis of novel pegylated 4-methylcoumarins. In: Journal of Macromolecular Science, Part A: Pure and Applied Chemistry. 2007 ; Vol. 44, No. 12. pp. 1293-1298.
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