Design and synthesis of novel pegylated 4-methylcoumarins

Mukesh K. Pandey, Rahul Tyagi, Shilpi Tomar, Jayant Kumar, Virinder S. Parmar, Arthur C. Watterson

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Coumarins are well known for their antioxidant and anti-edema activities. Their antioxidant property gets enhanced with a methyl group at the C-4 position of the pyran ring. To increase the antioxidant potential and their hydrophilicity, a lipase (Novozyme 435) catalyzed copolymerization of 4-methylcoumarin diesters and polyethylene glycols (PEGs) has been carried out to give novel copolymers.

Original languageEnglish (US)
Pages (from-to)1293-1298
Number of pages6
JournalJournal of Macromolecular Science, Part A: Pure and Applied Chemistry
Volume44
Issue number12
DOIs
StatePublished - Dec 1 2007

Keywords

  • 4-methylcoumarin
  • Antioxidant
  • Lipase
  • PEG

ASJC Scopus subject areas

  • Ceramics and Composites
  • Chemistry(all)
  • Polymers and Plastics
  • Materials Chemistry

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