TY - GEN
T1 - Design and initial performance evaluation of DbPET2, an intermediate generation breast PET prototype
AU - Ferrero, Andrea
AU - Peng, Qiyu
AU - Godinez, Felipe
AU - Chaudhari, Abhijit J.
AU - Vu, Chinh
AU - Choong, Woon Seng
AU - Moses, William W.
AU - Badawi, Ramsey D.
PY - 2011/1/1
Y1 - 2011/1/1
N2 - The combined effort of several laboratories at our institution resulted in the building of the first dedicated, breast PET/CT prototype. Ongoing clinical trials for breast cancer diagnosis and assessment of response to treatment underlined the need of a second generation prototype with improved sensitivity and spatial resolution. The goals of the new prototype are to reduce scan time and partial volume effects on quantitative measurements of small lesions. Several designs have been proposed by our group and are currently under investigation at different levels. In this work, we present the complete characterization of a detector module for an intermediate generation breast PET prototype, together with its design and assembly. The proposed design consists of two heads, shaped around the circumference of a circle of radius 26 cm. Each head is formed by 2 rows of 8 modules each, each module consisting in a 14x14 array of unpolished LSO crystals, read out by a position sensitive photomultiplier tube (PSPMT). Crystal pitch is 1.5 mm. A complete characterization of two detectors modules in coincidence resulted in an energy resolution of 25.2%, a timing resolution of 2.4 ns and an average intrinsic spatial resolution for a central row in the array of 1.26 mm. The two detector heads are now fully assembled and connected to the electronics suite for data processing. Modification of the system electronics is underways and the first floods, showing excellent position encoding, are presented. A thorough evaluation of system performance will be completed in the next few months. We plan to combine this scanner with a third generation breast CT system currently under parallel development to form a new generation, dedicated breast PET/CT scanner.
AB - The combined effort of several laboratories at our institution resulted in the building of the first dedicated, breast PET/CT prototype. Ongoing clinical trials for breast cancer diagnosis and assessment of response to treatment underlined the need of a second generation prototype with improved sensitivity and spatial resolution. The goals of the new prototype are to reduce scan time and partial volume effects on quantitative measurements of small lesions. Several designs have been proposed by our group and are currently under investigation at different levels. In this work, we present the complete characterization of a detector module for an intermediate generation breast PET prototype, together with its design and assembly. The proposed design consists of two heads, shaped around the circumference of a circle of radius 26 cm. Each head is formed by 2 rows of 8 modules each, each module consisting in a 14x14 array of unpolished LSO crystals, read out by a position sensitive photomultiplier tube (PSPMT). Crystal pitch is 1.5 mm. A complete characterization of two detectors modules in coincidence resulted in an energy resolution of 25.2%, a timing resolution of 2.4 ns and an average intrinsic spatial resolution for a central row in the array of 1.26 mm. The two detector heads are now fully assembled and connected to the electronics suite for data processing. Modification of the system electronics is underways and the first floods, showing excellent position encoding, are presented. A thorough evaluation of system performance will be completed in the next few months. We plan to combine this scanner with a third generation breast CT system currently under parallel development to form a new generation, dedicated breast PET/CT scanner.
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U2 - 10.1109/NSSMIC.2011.6152585
DO - 10.1109/NSSMIC.2011.6152585
M3 - Conference contribution
SN - 9781467301183
T3 - IEEE Nuclear Science Symposium Conference Record
SP - 3256
EP - 3259
BT - 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011
Y2 - 23 October 2011 through 29 October 2011
ER -