Denosumab-induced cutaneous hypersensitivity reaction with distinct clinical and histopathologic findings

Brian J. King; Julia S. Lehman; Julio C. Sartori Valinotti

doi:10.1111/cup.13070

Denosumab-induced cutaneous hypersensitivity reaction with distinct clinical and histopathologic findings

Brian J. King, Julia S. Lehman, Julio C. Sartori Valinotti

Dermatology

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Cutaneous reactions from targeted biologics are increasingly common. We describe a case of a cutaneous lichenoid drug eruption from the RANK inhibitor denosumab and a previously unreported lymphohistiocytic reaction pattern. The clinical and histopathological details of this case will aid in recognition, diagnosis, and treatment of drug rashes from denosumab.

Original language	English (US)
Pages (from-to)	156-158
Number of pages	3
Journal	Journal of Cutaneous Pathology
Volume	45
Issue number	2
DOIs	https://doi.org/10.1111/cup.13070
State	Published - Feb 1 2018

Keywords

cutaneous hypersensitivity
dermatopathology
drug eruption

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology
Dermatology

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10.1111/cup.13070

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title = "Denosumab-induced cutaneous hypersensitivity reaction with distinct clinical and histopathologic findings",

abstract = "Cutaneous reactions from targeted biologics are increasingly common. We describe a case of a cutaneous lichenoid drug eruption from the RANK inhibitor denosumab and a previously unreported lymphohistiocytic reaction pattern. The clinical and histopathological details of this case will aid in recognition, diagnosis, and treatment of drug rashes from denosumab.",

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AU - Lehman, Julia S.

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N2 - Cutaneous reactions from targeted biologics are increasingly common. We describe a case of a cutaneous lichenoid drug eruption from the RANK inhibitor denosumab and a previously unreported lymphohistiocytic reaction pattern. The clinical and histopathological details of this case will aid in recognition, diagnosis, and treatment of drug rashes from denosumab.

AB - Cutaneous reactions from targeted biologics are increasingly common. We describe a case of a cutaneous lichenoid drug eruption from the RANK inhibitor denosumab and a previously unreported lymphohistiocytic reaction pattern. The clinical and histopathological details of this case will aid in recognition, diagnosis, and treatment of drug rashes from denosumab.

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KW - drug eruption

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Denosumab-induced cutaneous hypersensitivity reaction with distinct clinical and histopathologic findings

Abstract

Keywords

ASJC Scopus subject areas

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