Denosumab-induced cutaneous hypersensitivity reaction with distinct clinical and histopathologic findings

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1 Scopus citations


Cutaneous reactions from targeted biologics are increasingly common. We describe a case of a cutaneous lichenoid drug eruption from the RANK inhibitor denosumab and a previously unreported lymphohistiocytic reaction pattern. The clinical and histopathological details of this case will aid in recognition, diagnosis, and treatment of drug rashes from denosumab.

Original languageEnglish (US)
Pages (from-to)156-158
Number of pages3
JournalJournal of Cutaneous Pathology
Issue number2
StatePublished - Feb 1 2018



  • cutaneous hypersensitivity
  • dermatopathology
  • drug eruption

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Dermatology

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