Demonstration of phase-assisted material decomposition with a Talbot-Lau interferometer using a single x-ray tube potential

E. R. Shanblatt, B. J. Nelson, S. Tao, S. Leng, C. H. McCollough

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We present a proof-of-principle demonstration of material decomposition using a single X-ray tube potential (38 kVp + 0.2 mm Sn, for an effective energy around 27 keV) with a Talbot-Lau grating-based phase-contrast computed tomography (CT) system. We show good material separation of water and fat and an accurate quantitative measurement of isopropyl alcohol. This method utilizes the distinctiveness of both components of the refractive index, δ and β, and is promising for separating soft tissue materials that have similar attenuation values such as water and fat.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2019
Subtitle of host publicationPhysics of Medical Imaging
EditorsHilde Bosmans, Guang-Hong Chen, Taly Gilat Schmidt
PublisherSPIE
ISBN (Electronic)9781510625433
DOIs
StatePublished - Jan 1 2019
EventMedical Imaging 2019: Physics of Medical Imaging - San Diego, United States
Duration: Feb 17 2019Feb 20 2019

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10948
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2019: Physics of Medical Imaging
CountryUnited States
CitySan Diego
Period2/17/192/20/19

Keywords

  • Material decomposition
  • Micro CT
  • Phase contrast

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Demonstration of phase-assisted material decomposition with a Talbot-Lau interferometer using a single x-ray tube potential'. Together they form a unique fingerprint.

  • Cite this

    Shanblatt, E. R., Nelson, B. J., Tao, S., Leng, S., & McCollough, C. H. (2019). Demonstration of phase-assisted material decomposition with a Talbot-Lau interferometer using a single x-ray tube potential. In H. Bosmans, G-H. Chen, & T. G. Schmidt (Eds.), Medical Imaging 2019: Physics of Medical Imaging [109482W] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10948). SPIE. https://doi.org/10.1117/12.2511806