Demonstration of phase-assisted material decomposition with a Talbot-Lau interferometer using a single x-ray tube potential

E. R. Shanblatt; B. J. Nelson; S. Tao; S. Leng; C. H. McCollough

doi:10.1117/12.2511806

Demonstration of phase-assisted material decomposition with a Talbot-Lau interferometer using a single x-ray tube potential

E. R. Shanblatt, B. J. Nelson, S. Tao, S. Leng, C. H. McCollough

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We present a proof-of-principle demonstration of material decomposition using a single X-ray tube potential (38 kVp + 0.2 mm Sn, for an effective energy around 27 keV) with a Talbot-Lau grating-based phase-contrast computed tomography (CT) system. We show good material separation of water and fat and an accurate quantitative measurement of isopropyl alcohol. This method utilizes the distinctiveness of both components of the refractive index, δ and β, and is promising for separating soft tissue materials that have similar attenuation values such as water and fat.

Original language	English (US)
Title of host publication	Medical Imaging 2019
Subtitle of host publication	Physics of Medical Imaging
Editors	Hilde Bosmans, Guang-Hong Chen, Taly Gilat Schmidt
Publisher	SPIE
ISBN (Electronic)	9781510625433
DOIs	https://doi.org/10.1117/12.2511806
State	Published - Jan 1 2019
Event	Medical Imaging 2019: Physics of Medical Imaging - San Diego, United States Duration: Feb 17 2019 → Feb 20 2019

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	10948
ISSN (Print)	1605-7422

Conference

Conference	Medical Imaging 2019: Physics of Medical Imaging
Country/Territory	United States
City	San Diego
Period	2/17/19 → 2/20/19

Keywords

Material decomposition
Micro CT
Phase contrast

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Biomaterials
Radiology Nuclear Medicine and imaging

Access to Document

10.1117/12.2511806

Cite this

Shanblatt, E. R., Nelson, B. J., Tao, S., Leng, S., & McCollough, C. H. (2019). Demonstration of phase-assisted material decomposition with a Talbot-Lau interferometer using a single x-ray tube potential. In H. Bosmans, G-H. Chen, & T. G. Schmidt (Eds.), Medical Imaging 2019: Physics of Medical Imaging [109482W] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10948). SPIE. https://doi.org/10.1117/12.2511806

Demonstration of phase-assisted material decomposition with a Talbot-Lau interferometer using a single x-ray tube potential. / Shanblatt, E. R.; Nelson, B. J.; Tao, S. et al.
Medical Imaging 2019: Physics of Medical Imaging. ed. / Hilde Bosmans; Guang-Hong Chen; Taly Gilat Schmidt. SPIE, 2019. 109482W (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10948).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Shanblatt, ER, Nelson, BJ, Tao, S, Leng, S & McCollough, CH 2019, Demonstration of phase-assisted material decomposition with a Talbot-Lau interferometer using a single x-ray tube potential. in H Bosmans, G-H Chen & TG Schmidt (eds), Medical Imaging 2019: Physics of Medical Imaging., 109482W, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10948, SPIE, Medical Imaging 2019: Physics of Medical Imaging, San Diego, United States, 2/17/19. https://doi.org/10.1117/12.2511806

Shanblatt ER, Nelson BJ, Tao S, Leng S , McCollough CH. Demonstration of phase-assisted material decomposition with a Talbot-Lau interferometer using a single x-ray tube potential. In Bosmans H, Chen G-H, Schmidt TG, editors, Medical Imaging 2019: Physics of Medical Imaging. SPIE. 2019. 109482W. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2511806

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AB - We present a proof-of-principle demonstration of material decomposition using a single X-ray tube potential (38 kVp + 0.2 mm Sn, for an effective energy around 27 keV) with a Talbot-Lau grating-based phase-contrast computed tomography (CT) system. We show good material separation of water and fat and an accurate quantitative measurement of isopropyl alcohol. This method utilizes the distinctiveness of both components of the refractive index, δ and β, and is promising for separating soft tissue materials that have similar attenuation values such as water and fat.

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Demonstration of phase-assisted material decomposition with a Talbot-Lau interferometer using a single x-ray tube potential

Abstract

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Keywords

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