Delayed radiation-induced bulbar palsy mimicking ALS

Susan A. Glenn, Mark A Ross

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

We describe a patient presenting with progressive bulbar dysfunction and spasticity that clinically mimicked amyotrophic lateral sclerosis (ALS). Electromyography, however, showed no evidence of denervation and revealed a rare combination of peripheral and central myokymia. We feel that this pattern of myokymia represented a marker of neural injury from remote radiation therapy. Nervous system disorders resulting from therapeutic radiation are described, and potential pathophysiologic mechanisms underlying myokymia are discussed. (C) 2000 John Wiley and Sons, Inc.

Original languageEnglish (US)
Pages (from-to)814-817
Number of pages4
JournalMuscle and Nerve
Volume23
Issue number5
DOIs
StatePublished - May 2000
Externally publishedYes

Fingerprint

Myokymia
Progressive Bulbar Palsy
Amyotrophic Lateral Sclerosis
Radiation
Electromyography
Denervation
Nervous System Diseases
Radiotherapy
Wounds and Injuries
Therapeutics

Keywords

  • Amyotrophic lateral sclerosis
  • Bulbar palsy
  • Myokymia
  • Radiation therapy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Delayed radiation-induced bulbar palsy mimicking ALS. / Glenn, Susan A.; Ross, Mark A.

In: Muscle and Nerve, Vol. 23, No. 5, 05.2000, p. 814-817.

Research output: Contribution to journalArticle

Glenn, Susan A. ; Ross, Mark A. / Delayed radiation-induced bulbar palsy mimicking ALS. In: Muscle and Nerve. 2000 ; Vol. 23, No. 5. pp. 814-817.
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