TY - JOUR
T1 - Degree of revascularization in patients with multivessel coronary disease
T2 - A report from the National Heart, Lung, and Blood Institute Percutaneous Transluminal Coronary Angioplasty Registry
AU - Reeder, G. S.
AU - Holmes, D. R.
AU - Detre, K.
AU - Costigan, T.
AU - Kelsey, S. F.
PY - 1988
Y1 - 1988
N2 - There is controversy regarding the application of angioplasty to patients with multivessel disease in whom all significant stenoses are not dilated. We analyzed the outcomes of 286 patients with multivessel disease and prior successful angioplasty at a mean follow-up duration of 26.2 months. End points analyzed included death, myocardial infarction, late revascularization, and angina pectoris. After successful angioplasty, 127 patiens had no residual stenoses of 70% or greater (group 1) and 159 patients had one or more residual stenoses or 70% of greater (group 2). Because there were significant differences in baseline risk factors between the two groups, a logistic regression model was used to make the necessary adjustments in the analysis. Adjusted estimates of the risk of death, death/myocardial infarction, or presence of angina pectoris did not differ between the two groups. Group 2 patients, however, had more coronary artery bypass surgery during follow-up, while those in group 1 had more second PTCA procedures. Results suggest that angioplasty can be safely applied to patients with multivessel disease, even when all significant stenoses are not dilated.
AB - There is controversy regarding the application of angioplasty to patients with multivessel disease in whom all significant stenoses are not dilated. We analyzed the outcomes of 286 patients with multivessel disease and prior successful angioplasty at a mean follow-up duration of 26.2 months. End points analyzed included death, myocardial infarction, late revascularization, and angina pectoris. After successful angioplasty, 127 patiens had no residual stenoses of 70% or greater (group 1) and 159 patients had one or more residual stenoses or 70% of greater (group 2). Because there were significant differences in baseline risk factors between the two groups, a logistic regression model was used to make the necessary adjustments in the analysis. Adjusted estimates of the risk of death, death/myocardial infarction, or presence of angina pectoris did not differ between the two groups. Group 2 patients, however, had more coronary artery bypass surgery during follow-up, while those in group 1 had more second PTCA procedures. Results suggest that angioplasty can be safely applied to patients with multivessel disease, even when all significant stenoses are not dilated.
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U2 - 10.1161/01.CIR.77.3.638
DO - 10.1161/01.CIR.77.3.638
M3 - Article
C2 - 2963707
AN - SCOPUS:0023849437
SN - 0009-7322
VL - 77
SP - 638
EP - 644
JO - Circulation
JF - Circulation
IS - 3
ER -