Patients presenting to the intensive care unit with liver failure may be categorized into two main subtypes, those with acute liver failure and those with complications of chronic liver diseases, the former being a rare condition and the latter far more common. In both categories, patients presenting with liver failure have phenotypical features of multi-system failure, a deranged inflammatory response, and pose unique challenges for management in the intensive care unit. Differentiating acute liver failure from the liver failure associated with chronic liver disease is of critical diagnostic importance, as management strategies are distinctly different. The purpose of this chapter is to review the definitions of liver failure, the epidemiology of liver disease, and current tools to aid in prognosis of liver failure.
- Acute liver failure
- Acute-on-chronic liver failure
ASJC Scopus subject areas