Definition, course, and outcome of mild cognitive impairment

Glenn E. Smith, Ronald C. Petersen, Joseph E. Parisi, Robert J. Ivnik, Emre Kokmen, Eric G. Tangalos, Stephen Waring

Research output: Contribution to journalArticle

156 Scopus citations


Mild Cognitive Impairment (MCI) is a term which can be applied to a boundary area between dementia and normal aging. Criteria which reliably describe persons falling in this range of the cognitive continuum can be defined. These persons are at very high risk for developing dementia. Biologic and cognitive parameters including Apolipoprotein E genotype help to differentiate MCI persons who will progress to dementia in 2-4 years from those who will remain free from dementia over this interval.

Original languageEnglish (US)
Pages (from-to)141-147
Number of pages7
JournalAging, Neuropsychology, and Cognition
Issue number2
StatePublished - Jun 1996


ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Experimental and Cognitive Psychology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

Cite this