Deep Venous Thrombosis and Pulmonary Embolism: Risk of Subsequent Malignant Neoplasms

Marie R. Griffin, Anthony W. Stanson, Manuel L. Brown, Mary F. Hauser, W. Michael O’fallon, Hazel M. Anderson, Francis J. Kazmier, L. Joseph Melton

Research output: Contribution to journalArticlepeer-review

102 Scopus citations

Abstract

We conducted a noncurrent prospective study of all Olmsted County, Minnesota, residents who had had a lowerextremity venogram, pulmonary angiogram, or lung scan performed because of suspicion of deep venous thrombosis or pulmonary emboli. One hundred thirteen cancer-free patients were followed for 386 person-years from the date of procedure. Nine subsequent cancers were observed compared with 4.5 expected (relative risk, 2.0; 95% confidence interval, 0.9 to 3.8), using total cancer incidence rates for the Rochester, Minn, population. Five hundred seventeen cancer-free controls were followed for 2072 person-years. Twenty subsequent cancers were observed compared with 11.6 expected, yielding a relative risk of 1.7 (95% confidence interval, 1.1 to 2.7). When cases and controls were compared directly, no statistically significant difference in cancer-free survival was found.

Original languageEnglish (US)
Pages (from-to)1907-1911
Number of pages5
JournalArchives of internal medicine
Volume147
Issue number11
DOIs
StatePublished - Nov 1987

ASJC Scopus subject areas

  • Internal Medicine

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