Deep brain stimulation

Technology at the cutting edge

Rahul S. Shah, Su-Youne Chang, Hoon Ki Min, Zang Hee Cho, Charles D. Blaha, Kendall H Lee

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Deep brain stimulation (DBS) surgery has been performed in over 75,000 people worldwide, and has been shown to be an effective treatment for Parkinson's disease, tremor, dystonia, epilepsy, depression, Tourette's syndrome, and obsessive compulsive disorder. We review current and em-erging evidence for the role of DBS in the management of a range of neurological and psychiatric conditions, and discuss the technical and practical aspects of performing DBS surgery. In the future, evolution of DBS technology may depend on several key areas, including better scientific understanding of its underlying mechanism of action, advances in high-spatial resolution imaging and development of novel electrophysiological and neurotransmitter microsensor systems. Such de-velopments could form the basis of an intelligent closed-loop DBS system with feedback-guided neuromodulation to optimize both electrode placement and therapeutic efficacy.

Original languageEnglish (US)
Pages (from-to)167-182
Number of pages16
JournalJournal of Clinical Neurology (Korea)
Volume6
Issue number4
DOIs
StatePublished - 2010

Fingerprint

Deep Brain Stimulation
Technology
Tourette Syndrome
Dystonia
Obsessive-Compulsive Disorder
Tremor
Neurotransmitter Agents
Parkinson Disease
Psychiatry
Epilepsy
Electrodes
Depression
Therapeutics

Keywords

  • Deep brain stimulation
  • Mechanism of action
  • Parkinson's disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Deep brain stimulation : Technology at the cutting edge. / Shah, Rahul S.; Chang, Su-Youne; Min, Hoon Ki; Cho, Zang Hee; Blaha, Charles D.; Lee, Kendall H.

In: Journal of Clinical Neurology (Korea), Vol. 6, No. 4, 2010, p. 167-182.

Research output: Contribution to journalArticle

Shah, Rahul S. ; Chang, Su-Youne ; Min, Hoon Ki ; Cho, Zang Hee ; Blaha, Charles D. ; Lee, Kendall H. / Deep brain stimulation : Technology at the cutting edge. In: Journal of Clinical Neurology (Korea). 2010 ; Vol. 6, No. 4. pp. 167-182.
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