TY - BOOK
T1 - Deep brain stimulation
T2 - Indications and applications
AU - Lee, Kendall H.
AU - Duffy, Penelope S.
AU - Bieber, Allan J.
N1 - Publisher Copyright:
© 2017 Pan Stanford Publishing Pte. Ltd. All rights reserved.
PY - 2016/12/8
Y1 - 2016/12/8
N2 - Deep brain stimulation (DBS) is a widely used therapy for movement disorders such as Parkinson's disease, essential tremor, and dystonia. Its therapeutic success has led to the application of DBS for an increasing spectrum of conditions. However, the fundamental relationships between neural activation, neurochemical transmission, and clinical outcomes during DBS are not well understood. Drawing on the clinical and research expertise of the Mayo Clinic Neural Engineering Laboratories, this book addresses the history of therapeutic electrical stimulation of the brain, its current application and outcomes, and theories about its underlying mechanisms. It reviews research on measures of local stimulationevoked neurochemical release, imaging research on stimulation-induced neural circuitry activation, and the state of the art on closed-loop feedback devices for stimulation delivery.
AB - Deep brain stimulation (DBS) is a widely used therapy for movement disorders such as Parkinson's disease, essential tremor, and dystonia. Its therapeutic success has led to the application of DBS for an increasing spectrum of conditions. However, the fundamental relationships between neural activation, neurochemical transmission, and clinical outcomes during DBS are not well understood. Drawing on the clinical and research expertise of the Mayo Clinic Neural Engineering Laboratories, this book addresses the history of therapeutic electrical stimulation of the brain, its current application and outcomes, and theories about its underlying mechanisms. It reviews research on measures of local stimulationevoked neurochemical release, imaging research on stimulation-induced neural circuitry activation, and the state of the art on closed-loop feedback devices for stimulation delivery.
UR - http://www.scopus.com/inward/record.url?scp=85052715023&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85052715023&partnerID=8YFLogxK
U2 - 10.1201/9781315364759
DO - 10.1201/9781315364759
M3 - Book
AN - SCOPUS:85052715023
SN - 9789814669894
BT - Deep brain stimulation
PB - Pan Stanford Publishing Pte. Ltd.
ER -