TY - JOUR
T1 - Dedifferentiated liposarcoma of the esophagus
T2 - A case report and selected review of the literature
AU - Brett, Christopher L.
AU - Miller, Daniel H.
AU - Jiang, Liuyan
AU - Wolfsen, Herbert C.
AU - Attia, Steven
AU - Hintenlang, Lauren
AU - Jagadesh, Niveditha
AU - Miller, Robert C.
N1 - Publisher Copyright:
© C.L. Brett et al., 2016 Licensee PAGEPress, Italy.
PY - 2016/12/20
Y1 - 2016/12/20
N2 - Soft tissue sarcomas of the esophagus represent an extremely rare cause of esophageal masses, and an even smaller proportion of these tumors represent dedifferentiated liposarcomas. We present a case of a 75-yearold gentleman presenting with dysphagia found to have a 5 cm pedunculated mass in the cervical esophagus, originating at the cricopharyngeus. This was found to have involvement limited to the superficial mucosa by endoscopic ultrasound, and the lesion was subsequently resected endoscopically. Pathology demonstrated an undifferentiated pleomorphic sarcoma later determined to represent dedifferentiated liposarcoma after fluorescence in situ hybridization analysis. The patient received no additional adjuvant therapy and remains disease free 20 months from the procedure. While treatment experience is limited, our case demonstrates that in selected patients, sustained local control can be obtained without radical resection.
AB - Soft tissue sarcomas of the esophagus represent an extremely rare cause of esophageal masses, and an even smaller proportion of these tumors represent dedifferentiated liposarcomas. We present a case of a 75-yearold gentleman presenting with dysphagia found to have a 5 cm pedunculated mass in the cervical esophagus, originating at the cricopharyngeus. This was found to have involvement limited to the superficial mucosa by endoscopic ultrasound, and the lesion was subsequently resected endoscopically. Pathology demonstrated an undifferentiated pleomorphic sarcoma later determined to represent dedifferentiated liposarcoma after fluorescence in situ hybridization analysis. The patient received no additional adjuvant therapy and remains disease free 20 months from the procedure. While treatment experience is limited, our case demonstrates that in selected patients, sustained local control can be obtained without radical resection.
KW - Dedifferentiated liposarcoma
KW - Esophageal mass
KW - Surgical resection
KW - Undifferentiated pleomorphic sarcoma
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U2 - 10.4081/rt.2016.6791
DO - 10.4081/rt.2016.6791
M3 - Review article
AN - SCOPUS:85007237307
SN - 2036-3605
VL - 8
SP - 201
EP - 202
JO - Rare Tumors
JF - Rare Tumors
IS - 4
M1 - 6791
ER -