De Novo Malignancies After Transplantation. Risk and Surveillance Strategies

Iliana Doycheva, Syed Amer, Kymberly D. Watt

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

De novo malignancies are one of the leading causes of late mortality after liver and kidney transplantation. Nonmelanoma skin cancer is the most common malignancy, followed by posttransplant lymphoproliferative disorder and solid organ tumors. Immunosuppression is a key factor for cancer development, although many other transplant-related and traditional risk factors also play a role. In this review, the authors summarize risk factors and outcomes of frequently encountered de novo malignancies after liver and kidney transplantation to stratify recipients at highest risk. Future efforts in prospectively validated, cost-effective surveillance strategies that improve survival of these complex patients are greatly needed.

Original languageEnglish (US)
JournalMedical Clinics of North America
DOIs
StateAccepted/In press - 2016

Fingerprint

Transplantation
Neoplasms
Liver Transplantation
Kidney Transplantation
Lymphoproliferative Disorders
Skin Neoplasms
Immunosuppression
Transplants
Costs and Cost Analysis
Survival
Mortality

Keywords

  • Incidence
  • Mortality
  • Posttransplant lymphoproliferative disorder
  • Risk factors
  • Skin cancer
  • Solid organ tumors
  • Surveillance

ASJC Scopus subject areas

  • Medicine(all)

Cite this

De Novo Malignancies After Transplantation. Risk and Surveillance Strategies. / Doycheva, Iliana; Amer, Syed; Watt, Kymberly D.

In: Medical Clinics of North America, 2016.

Research output: Contribution to journalArticle

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