Dataset of TWIST1-regulated genes in the cranial mesoderm and a transcriptome comparison of cranial mesoderm and cranial neural crest

Heidi Bildsoe, Xiaochen Fan, Emilie E. Wilkie, Ator Ashoti, Vanessa J. Jones, Melinda Power, Jing Qin, Junwen Wang, Patrick P.L. Tam, David A.F. Loebel

Research output: Contribution to journalArticlepeer-review

Abstract

This article contains data related to the research article entitled “Transcriptional targets of TWIST1 in the cranial mesoderm regulate cell-matrix interactions and mesenchyme maintenance” by Bildsoe et al. (2016) [1]. The data presented here are derived from: (1) a microarray-based comparison of sorted cranial mesoderm (CM) and cranial neural crest (CNC) cells from E9.5 mouse embryos; (2) comparisons of transcription profiles of head tissues from mouse embryos with a CM-specific loss-of-function of Twist1 and control mouse embryos collected at E8.5 and E9.5; (3) ChIP-seq using a TWIST1-specific monoclonal antibody with chromatin extracts from TWIST1-expressing MDCK cells, a model for a TWIST1-dependent mesenchymal state.

Original languageEnglish (US)
Pages (from-to)372-375
Number of pages4
JournalData in Brief
Volume9
DOIs
StatePublished - Dec 2016

Keywords

  • ChIP-seq
  • Cranial mesenchyme
  • Craniofacial
  • Embryo
  • Transcriptional target
  • Twist1

ASJC Scopus subject areas

  • General

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