Darunavir

Wissam I. El-Atrouni; Zelalem Temesgen

doi:10.1358/dot.2007.43.10.1131764

Darunavir

Wissam I. El-Atrouni, Zelalem Temesgen

Infectious Diseases

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

Darunavir is a nonpeptidic protease inhibitor recently approved for the treatment of antiretroviral therapy-experienced patients. It has potent in vitro activity against viral isolates that are resistant to currently licensed protease inhibitors. In randomized clinical trials with optimized background regimens, it has shown virologic and immunologic responses superior to comparator-based regimens.

Original language	English (US)
Pages (from-to)	671-679
Number of pages	9
Journal	Drugs of Today
Volume	43
Issue number	10
DOIs	https://doi.org/10.1358/dot.2007.43.10.1131764
State	Published - Oct 1 2007

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)

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10.1358/dot.2007.43.10.1131764

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title = "Darunavir",

abstract = "Darunavir is a nonpeptidic protease inhibitor recently approved for the treatment of antiretroviral therapy-experienced patients. It has potent in vitro activity against viral isolates that are resistant to currently licensed protease inhibitors. In randomized clinical trials with optimized background regimens, it has shown virologic and immunologic responses superior to comparator-based regimens.",

author = "El-Atrouni, {Wissam I.} and Zelalem Temesgen",

year = "2007",

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AU - El-Atrouni, Wissam I.

AU - Temesgen, Zelalem

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N2 - Darunavir is a nonpeptidic protease inhibitor recently approved for the treatment of antiretroviral therapy-experienced patients. It has potent in vitro activity against viral isolates that are resistant to currently licensed protease inhibitors. In randomized clinical trials with optimized background regimens, it has shown virologic and immunologic responses superior to comparator-based regimens.

AB - Darunavir is a nonpeptidic protease inhibitor recently approved for the treatment of antiretroviral therapy-experienced patients. It has potent in vitro activity against viral isolates that are resistant to currently licensed protease inhibitors. In randomized clinical trials with optimized background regimens, it has shown virologic and immunologic responses superior to comparator-based regimens.

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M3 - Review article

C2 - 17987220

AN - SCOPUS:36849050220

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VL - 43

SP - 671

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Darunavir

Abstract

ASJC Scopus subject areas

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