Danish-American Family (Family E) with 'Parkinson's Diseasé: Pitfalls of Genetic Studies

Zbigniew K. Wszolek; Ronald F. Pfeiffer; Melody A. Denson; Rodney D. Mccomb

doi:10.1016/1353-8020(95)00023-2

Danish-American Family (Family E) with 'Parkinson's Diseasé: Pitfalls of Genetic Studies

Zbigniew K. Wszolek, Ronald F. Pfeiffer, Melody A. Denson, Rodney D. Mccomb

Neurology

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Clinical and genetic investigations were undertaken to evaluate a large Danish-American kindred with a possible autosomal dominant parkinsonian syndrome (PS) as indicated by the index case. After full investigation of available data a suspected autosomal dominant inheritance pattern of PS could not be confirmed. However, it is possible that this kindred represents familial tremor. Longitudinal clinical observations on this family are planned.

Original language	English (US)
Pages (from-to)	47-49
Number of pages	3
Journal	Parkinsonism and Related Disorders
Volume	2
Issue number	1
DOIs	https://doi.org/10.1016/1353-8020(95)00023-2
State	Published - Jan 1996

Keywords

Familial tremor
Genetic studies
Inherited parkinsonism

ASJC Scopus subject areas

Neurology
Geriatrics and Gerontology
Clinical Neurology

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10.1016/1353-8020(95)00023-2

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title = "Danish-American Family (Family E) with 'Parkinson's Diseas{\'e}: Pitfalls of Genetic Studies",

abstract = "Clinical and genetic investigations were undertaken to evaluate a large Danish-American kindred with a possible autosomal dominant parkinsonian syndrome (PS) as indicated by the index case. After full investigation of available data a suspected autosomal dominant inheritance pattern of PS could not be confirmed. However, it is possible that this kindred represents familial tremor. Longitudinal clinical observations on this family are planned.",

keywords = "Familial tremor, Genetic studies, Inherited parkinsonism",

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T2 - Pitfalls of Genetic Studies

AU - Wszolek, Zbigniew K.

AU - Pfeiffer, Ronald F.

AU - Denson, Melody A.

AU - Mccomb, Rodney D.

PY - 1996/1

Y1 - 1996/1

N2 - Clinical and genetic investigations were undertaken to evaluate a large Danish-American kindred with a possible autosomal dominant parkinsonian syndrome (PS) as indicated by the index case. After full investigation of available data a suspected autosomal dominant inheritance pattern of PS could not be confirmed. However, it is possible that this kindred represents familial tremor. Longitudinal clinical observations on this family are planned.

AB - Clinical and genetic investigations were undertaken to evaluate a large Danish-American kindred with a possible autosomal dominant parkinsonian syndrome (PS) as indicated by the index case. After full investigation of available data a suspected autosomal dominant inheritance pattern of PS could not be confirmed. However, it is possible that this kindred represents familial tremor. Longitudinal clinical observations on this family are planned.

KW - Familial tremor

KW - Genetic studies

KW - Inherited parkinsonism

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Danish-American Family (Family E) with 'Parkinson's Diseasé: Pitfalls of Genetic Studies

Abstract

Keywords

ASJC Scopus subject areas

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