Abstract
In an effort to determine the effect of cytoreductive surgery on the metastatic process, MAT‐LyLu flank tumors were excised from Copenhagen X Fischer rats and the effects of this surgery on metastatic lung lesions were observed. Cytoreduction resulted in a decrease in lung lesions (P < 0.05). Adjuvant cyclophosphamide (CTX) further enhanced this beneficial effect. A concurrent increase in the helper/suppressor ratios suggested that this beneficial response might be mediated by the host's immune response.
Original language | English (US) |
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Pages (from-to) | 122-126 |
Number of pages | 5 |
Journal | Journal of Surgical Oncology |
Volume | 48 |
Issue number | 2 |
DOIs | |
State | Published - Oct 1991 |
Keywords
- adjuvant chemotherapy
- immune potentiation
- therapy
ASJC Scopus subject areas
- Surgery
- Oncology