Current trends in the management of extra-abdominal desmoid tumours

Panayiotis J. Papagelopoulos, Andreas F. Mavrogenis, Evanthia A. Mitsiokapa, Kleo Th Papaparaskeva, Evanthia Galanis, Panayotis N. Soucacos

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Extra-abdominal desmoid tumours are slow-growing, histologically benign tumours of fibroblastic origin with variable biologic behaviour. They are locally aggressive and invasive to surrounding anatomic structures. Magnetic resonance imaging is the modality of choice for the diagnosis and the evaluation of the tumours. Current management of desmoids involves a multidisciplinary approach. Wide margin surgical resection remains the main treatment modality for local control of the tumour. Amputation should not be the initial treatment, and function-preserving procedures should be the primary treatment goal. Adjuvant radiation therapy is recommended both for primary and recurrent lesions. Chemotherapy may be used for recurrent or unresectable disease. Overall local recurrence rates vary and depend on patient's age, tumour location and margins at resection.

Original languageEnglish (US)
Article number21
JournalWorld Journal of Surgical Oncology
Volume4
DOIs
StatePublished - Apr 3 2006

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Aggressive Fibromatosis
Neoplasms
Amputation
Radiotherapy
Therapeutics
Magnetic Resonance Imaging
Recurrence
Drug Therapy
Margins of Excision

ASJC Scopus subject areas

  • Cancer Research
  • Surgery

Cite this

Papagelopoulos, P. J., Mavrogenis, A. F., Mitsiokapa, E. A., Papaparaskeva, K. T., Galanis, E., & Soucacos, P. N. (2006). Current trends in the management of extra-abdominal desmoid tumours. World Journal of Surgical Oncology, 4, [21]. https://doi.org/10.1186/1477-7819-4-21

Current trends in the management of extra-abdominal desmoid tumours. / Papagelopoulos, Panayiotis J.; Mavrogenis, Andreas F.; Mitsiokapa, Evanthia A.; Papaparaskeva, Kleo Th; Galanis, Evanthia; Soucacos, Panayotis N.

In: World Journal of Surgical Oncology, Vol. 4, 21, 03.04.2006.

Research output: Contribution to journalArticle

Papagelopoulos, PJ, Mavrogenis, AF, Mitsiokapa, EA, Papaparaskeva, KT, Galanis, E & Soucacos, PN 2006, 'Current trends in the management of extra-abdominal desmoid tumours', World Journal of Surgical Oncology, vol. 4, 21. https://doi.org/10.1186/1477-7819-4-21
Papagelopoulos PJ, Mavrogenis AF, Mitsiokapa EA, Papaparaskeva KT, Galanis E, Soucacos PN. Current trends in the management of extra-abdominal desmoid tumours. World Journal of Surgical Oncology. 2006 Apr 3;4. 21. https://doi.org/10.1186/1477-7819-4-21
Papagelopoulos, Panayiotis J. ; Mavrogenis, Andreas F. ; Mitsiokapa, Evanthia A. ; Papaparaskeva, Kleo Th ; Galanis, Evanthia ; Soucacos, Panayotis N. / Current trends in the management of extra-abdominal desmoid tumours. In: World Journal of Surgical Oncology. 2006 ; Vol. 4.
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