Current trends in the management of extra-abdominal desmoid tumours

Panayiotis J. Papagelopoulos, Andreas F. Mavrogenis, Evanthia A. Mitsiokapa, Kleo Th Papaparaskeva, Evanthia C. Galanis, Panayotis N. Soucacos

Research output: Contribution to journalReview article

48 Scopus citations

Abstract

Extra-abdominal desmoid tumours are slow-growing, histologically benign tumours of fibroblastic origin with variable biologic behaviour. They are locally aggressive and invasive to surrounding anatomic structures. Magnetic resonance imaging is the modality of choice for the diagnosis and the evaluation of the tumours. Current management of desmoids involves a multidisciplinary approach. Wide margin surgical resection remains the main treatment modality for local control of the tumour. Amputation should not be the initial treatment, and function-preserving procedures should be the primary treatment goal. Adjuvant radiation therapy is recommended both for primary and recurrent lesions. Chemotherapy may be used for recurrent or unresectable disease. Overall local recurrence rates vary and depend on patient's age, tumour location and margins at resection.

Original languageEnglish (US)
Article number21
JournalWorld Journal of Surgical Oncology
Volume4
DOIs
StatePublished - Apr 3 2006

ASJC Scopus subject areas

  • Surgery
  • Oncology

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    Papagelopoulos, P. J., Mavrogenis, A. F., Mitsiokapa, E. A., Papaparaskeva, K. T., Galanis, E. C., & Soucacos, P. N. (2006). Current trends in the management of extra-abdominal desmoid tumours. World Journal of Surgical Oncology, 4, [21]. https://doi.org/10.1186/1477-7819-4-21