Current status of stem cell mobilization: Review

Research output: Contribution to journalReview article

106 Scopus citations

Abstract

New advances in effective mobilization of peripheral blood stem cells have permitted a greater proportion of patients to benefit from autologous stem cell transplantation. In this review, the relative merits of peripheral blood and mobilized bone marrow are discussed. All available agents are reviewed. A critical assessment of the appropriate dosing and frequency of available growth factors is undertaken, and the most commonly used chemotherapy plus growth factor combinations are covered. Specific recommendations for patients who are poor mobilizers are dealt with including the role of plerixafor.

Original languageEnglish (US)
Pages (from-to)647-662
Number of pages16
JournalBritish journal of haematology
Volume150
Issue number6
DOIs
StatePublished - Sep 1 2010

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Keywords

  • growth factors
  • mobilization
  • multiple myeloma
  • non-Hodgkin lymphoma
  • stem cell transplantation

ASJC Scopus subject areas

  • Hematology

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